Protein Alignment ZnT86D and Slc30a7

DIOPT Version :10

• Sequence 1: NP_650049.1
• Gene: ZnT86D / 41342
• FlyBaseID: FBgn0037875
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_075703.1
• Gene: Slc30a7 / 66500
• MGIID: 1913750
• Length: 378
• Species: Mus musculus
• Alignment Length: 380
• Identity: 233/380 - (61%)
• Similarity: 284/380 - (74%)
• Gaps: 20/380 - (5%)

  Fly     1 MIPLSHKD--RSSLGYRIREKLNSWKRLIFSDRNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLI 63
            |:|||.||  .....:.:..|::.|.|.|.||:.|||||.||.||||||||||.|||.:|.||||
Mouse     1 MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLI 65

  Fly    64 SDSFHMFFDCTGLLAGLAASVITKWKANDKFSYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERL 128
            |||||||||.|.:|||||||||:||:.||.||||||||||||||||.|||:|.||||.||||||.
Mouse    66 SDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERA 130

  Fly   129 IEPPEVKHERLFVVSVLGLLVNLVGIYAFNHGGHGHSHG-GHGHSHGGGHGH-GHSHGHTDAGNH 191
            :.||:|.||||.:||:||.:||||||:.||||||||||| ||||||...:|. .|||||.| ..|
Mouse   131 LAPPDVHHERLLLVSILGFVVNLVGIFVFNHGGHGHSHGSGHGHSHSLFNGALDHSHGHED-HCH 194

  Fly   192 NHQAITLDNGHGHSHDHDSHGHSHGDM-----------SGSNSQIMRGVFLHILADTLGSVGVII 245
            :|:|   .:|..|||||| |.|.||.:           :|.:.||::|||||||||||||:|||.
Mouse   195 SHEA---KHGAAHSHDHD-HAHGHGHLHSHDGPSFKATAGPSRQILQGVFLHILADTLGSIGVIA 255

  Fly   246 SAVLMHMFGWMIADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTGLAGV 310
            ||::|..||.|||||||||.||:||.:||:.|::||:.|||||.|..|:.:||||||:|..|.||
Mouse   256 SAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPSLENTLPQCYQRVQQLQGV 320

  Fly   311 YAVQEPHFWTLCSDVYVGALKLEVSKNVDPKYVVTHTRMIFEAVGVKQIYIQLDY 365
            |.:||.||||||||||||.|||.|:.:.|.:::::.|..||...||:|:|:|:|:
Mouse   321 YNLQEQHFWTLCSDVYVGTLKLVVAPDADARWILSQTHNIFTQAGVRQLYVQIDF 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT86D	NP_650049.1	CzcD	45..365	CDD:440843	210/332 (63%)
Slc30a7	NP_075703.1	CzcD	31..356	CDD:440843	214/329 (65%)
		His-rich loop	161..220		36/63 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..224		19/42 (45%)