Protein Alignment ZnT86D and Slc30a4

DIOPT Version :10

• Sequence 1: NP_650049.1
• Gene: ZnT86D / 41342
• FlyBaseID: FBgn0037875
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_742063.2
• Gene: Slc30a4 / 64469
• RGDID: 619750
• Length: 430
• Species: Rattus norvegicus
• Alignment Length: 369
• Identity: 92/369 - (24%)
• Similarity: 179/369 - (48%)
• Gaps: 45/369 - (12%)

  Fly     2 IPLSHKDRSSLGYRIREKLNSWKR--LIFSDRNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLIS 64
            :||::   |.|..::....|..||  |:...:....|.:..:|.|.|...||..|.:.|||.:::
  Rat    81 LPLTN---SQLSLKMDPCDNCSKRRELLKQRKVKTRLTIAAVLYLLFMIGELVGGYMANSLAIMT 142

  Fly    65 DSFHMFFDCTGLLAGLAASVITKWKANDKFSYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERLI 129
            |:.||..|.:.::..|.|..::......:|::|:.|.|||:..::.:.:..:..|:|.|.|:|.|
  Rat   143 DALHMLTDLSAIILTLLALWLSSKSPTRRFTFGFHRLEVLSAMISVMLVYVLMGFLLYEAVQRTI 207

  Fly   130 EPP-EVKHERLFVVSVLGLLVNLVGIYAFNHGGHGHSHGGHGHSHGGGHGHGHSHGHTDAGNHNH 193
            ... |:..:.:.:.:.:|:.||::..:..|..||.||               |:|.|:...|
  Rat   208 HMNYEINGDVMLITAAVGVAVNVIMGFLLNQSGHHHS---------------HAHSHSLPSN--- 254

  Fly   194 QAITLDNGHGHSHDHDSHGHSHGDMSGSNSQIMRGVFLHILADTLGSVGVIISAVLMHMF-GWMI 257
                       |....|.||||    |.:|..:|..|:|.|.|.:.||||:|:|.::... .:.|
  Rat   255 -----------SPSMVSSGHSH----GQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYKI 304

  Fly   258 ADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTGLAGVYAVQEPHFWTLC 322
            |||||:...:||:|.:.|.:|.::::|:::..|:.|  ::....:.:..:..||:|::.:.|:|.
  Rat   305 ADPICTYIFSLLVAFTTLRIIWDTVVIILEGVPSHL--NVDYIKESLMKIEDVYSVEDLNIWSLT 367

  Fly   323 SDVYVGALKLEVSKNVDPKYVVTHTR---MIFEAVGVKQIYIQL 363
            |......:.:::......|:....::   ::....|:.:..:||
  Rat   368 SGKATAIVHMQLIPGSSSKWEEVQSKAKHLLLNTFGMYKCTVQL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT86D	NP_650049.1	CzcD	45..365	CDD:440843	81/324 (25%)
Slc30a4	NP_742063.2	CDF	123..414	CDD:273544	81/324 (25%)
		Zinc binding. /evidence=ECO:0000269|PubMed:10600821	240..265		12/53 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..265		8/33 (24%)