Protein Alignment ZnT86D and Slc30a4

DIOPT Version :9

• Sequence 1: NP_650049.1
• Gene: ZnT86D / 41342
• FlyBaseID: FBgn0037875
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_035904.2
• Gene: Slc30a4 / 22785
• MGIID: 1345282
• Length: 430
• Species: Mus musculus
• Alignment Length: 369
• Identity: 91/369 - (24%)
• Similarity: 178/369 - (48%)
• Gaps: 45/369 - (12%)

  Fly     2 IPLSHKDRSSLGYRIREKLNSWKR--LIFSDRNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLIS 64
            :||::   |.|..::....|..||  |:...:....|.:..:|.|.|...||..|.:.|||.:::
Mouse    81 LPLTN---SQLSLKMDPCDNCSKRRELLKQRKVKTRLTIAAVLYLLFMIGELVGGYMANSLAIMT 142

  Fly    65 DSFHMFFDCTGLLAGLAASVITKWKANDKFSYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERLI 129
            |:.||..|.:.::..|.|..::......:|::|:.|.|||:..::.:.:..:..|:|.|.|:|.|
Mouse   143 DALHMLTDLSAIILTLLALWLSSKSPTRRFTFGFHRLEVLSAMISVMLVYVLMGFLLYEAVQRTI 207

  Fly   130 EPP-EVKHERLFVVSVLGLLVNLVGIYAFNHGGHGHSHGGHGHSHGGGHGHGHSHGHTDAGNHNH 193
            ... |:..:.:.:.:.:|:.||::..:..|..||.||               |:|.|:...|
Mouse   208 HMNYEINGDVMLITAAVGVAVNVIMGFLLNQSGHHHS---------------HAHSHSLPSN--- 254

  Fly   194 QAITLDNGHGHSHDHDSHGHSHGDMSGSNSQIMRGVFLHILADTLGSVGVIISAVLMHMF-GWMI 257
                       |....|.||:|    |.:|..:|..|:|.|.|.:.||||:|:|.::... .:.|
Mouse   255 -----------SPSMVSSGHNH----GQDSLAVRAAFVHALGDLVQSVGVLIAAYIIRFKPEYKI 304

  Fly   258 ADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTGLAGVYAVQEPHFWTLC 322
            |||||:...:||:|.:...:|.::::|:::..|:.|  ::....:.:..:..||:|::.:.|:|.
Mouse   305 ADPICTYIFSLLVAFTTFRIIWDTVVIILEGVPSHL--NVDYIKESLMKIEDVYSVEDLNIWSLT 367

  Fly   323 SDVYVGALKLEVSKNVDPKYVVTHTR---MIFEAVGVKQIYIQL 363
            |......:.:::......|:....::   ::....|:.:..|||
Mouse   368 SGKSTAIVHMQLIPGSSSKWEEVQSKAKHLLLNTFGMYKCTIQL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZnT86D	NP_650049.1	CDF	46..366	CDD:273544	80/323 (25%)
		Cation_efflux	46..286	CDD:279834	67/241 (28%)
Slc30a4	NP_035904.2	CDF	123..414	CDD:273544	80/324 (25%)
		Cation_efflux	123..333	CDD:279834	67/242 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..264		7/32 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1230
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810