DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZnT86D and toc-1

DIOPT Version :9

Sequence 1:	NP_650049.1	Gene:	ZnT86D / 41342	FlyBaseID:	FBgn0037875	Length:	366	Species:	Drosophila melanogaster
Sequence 2:	NP_001367624.1	Gene:	toc-1 / 175728	WormBaseID:	WBGene00006590	Length:	446	Species:	Caenorhabditis elegans

Alignment Length:	373	Identity:	83/373 - (22%)
Similarity:	142/373 - (38%)	Gaps:	74/373 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 IREKLN----------SW-KRLIFSDRNSRNLFLFLLLNLSFAFVELFYGIVTNSLGLISDSFHM 69
            :::.||          || .|.:...:..|.| :..|:.|:...:..:....::|:.|:|..:..
Worm     7 LKKNLNRVDFHSMVSFSWVSRSLHHPQGKRGL-ISTLICLACVGILAYCVSTSHSIVLMSTLWIT 70

  Fly    70 FFDCTGLLAGLAASVITKWKANDKFSYGYVRAEVLAGFVNSLFLLFIAFFILSEGVERLIEP--- 131
            .|......|.|.:..||: |...|||||..|..|||.|..::.....:.|:..|..|.|:.|
Worm    71 IFSFCSQFASLYSMSITE-KPTHKFSYGLARVPVLAVFSTTVLAQLFSIFLSKESFEHLLSPDHH 134

  Fly   132 ----PEVKHER---------LFVVSVLGLLVNLVGIYAFNHGGHGHSHGGHGHSHGGGHGHGHSH 183
                ....||.         .||.|....:..|:..||..:
Worm   135 GSHDASAAHEHEVEEIGGWPYFVGSAASSVALLLSAYALKN------------------------ 175

  Fly   184 GHTDAGNHNHQAITLDNGHGHSHDHDSH-------GHSHGDMSGSNSQIMRGVFLHILADTLGSV 241
               ....|..|:.|..:...|:.|. ||       |.|...:...||.:       :||.|...:
Worm   176 ---QPFQHVLQSATASSLQEHAADL-SHAVCWVIPGLSRLLLPRINSMV-------LLALTTTGL 229

  Fly   242 GVIISAVLMHMFGWMIADPICSIFIALLIALSVLSLIKESIMILMQRQPADLDRSLPQCYQKVTG 306
            .::... ..|.|.|  |||:|.:.:::.:..::..|...:.|||:|..|..|...:.:|..:.:.
Worm   230 NLLCEH-FKHDFAW--ADPVCCLLLSVAVFSTMYPLSTYTGMILLQTTPPHLINQIDRCISEASH 291

  Fly   307 LAGVYAVQEPHFWTLCSDVYVGALKLEVSKNVDPKYVVTHTRMIFEAV 354
            :.||..::...||.|..:..||.:.:.|.::.|.:.|:.|....|.:|
Worm   292 IDGVLELKSGRFWQLDFNSLVGTVDVRVRRDADEQNVLAHVTEKFSSV 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZnT86D	NP_650049.1	CDF	46..366	CDD:273544	74/332 (22%)
ZnT86D	NP_650049.1	Cation_efflux	46..286	CDD:279834	56/262 (21%)
toc-1	NP_001367624.1	Cation_efflux	45..271	CDD:396224	57/264 (22%)
toc-1	NP_001367624.1	ureE	<378..441	CDD:237323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910