Protein Alignment Tctp and Tpt1

DIOPT Version :10

• Sequence 1: NP_650048.1
• Gene: Tctp / 41341
• FlyBaseID: FBgn0037874
• Length: 172
• Species: Drosophila melanogaster
• Sequence 2: NP_033455.1
• Gene: Tpt1 / 22070
• MGIID: 104890
• Length: 172
• Species: Mus musculus
• Alignment Length: 178
• Identity: 87/178 - (48%)
• Similarity: 121/178 - (67%)
• Gaps: 12/178 - (6%)

  Fly     1 MKIYKDIITGDEMFADTYKMK-LVDDVIYEVYGKLITR-QG--DDIKLEGANASAEEAD-EGTDI 60
            |.||:|:|:.||:|:|.||:: :.|.:..||.||:::| :|  || .|.|.|||||..: |||:.
Mouse     1 MIIYRDLISHDELFSDIYKIREIADGLCLEVEGKMVSRTEGAIDD-SLIGGNASAEGPEGEGTES 64

  Fly    61 TSESGVDVVLNHRLTECFAFGDKKSYTLYLKDYMKKVLAKLEEKSPDQVDIFKTNMNKAMKDILG 125
            |..:|||:|:||.|.|. :| .|::|..|:|||||.:..||||:.|::|..|.|...:.:|.||.
Mouse    65 TVVTGVDIVMNHHLQET-SF-TKEAYKKYIKDYMKSLKGKLEEQKPERVKPFMTGAAEQIKHILA 127

  Fly   126 RFKELQFFTGESMDCDGMVALVEYREINGDSV-PVLMFFKHGLEEEKC 172
            .|...|||.||:|:.||||||::|||   |.| |.::|||.|||.|||
Mouse   128 NFNNYQFFIGENMNPDGMVALLDYRE---DGVTPFMIFFKDGLEMEKC 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tctp	NP_650048.1	TCTP	1..167	CDD:459957	81/171 (47%)
Tpt1	NP_033455.1	TCTP	1..167	CDD:459957	81/171 (47%)
		Required for reduction of TSC22D1 protein stability. /evidence=ECO:0000250|UniProtKB:P13693	70..172		53/106 (50%)