Protein Alignment cu and NGL3

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_013588.1
• Gene: NGL3 / 854921
• SGDID: S000004587
• Length: 505
• Species: Saccharomyces cerevisiae
• Alignment Length: 525
• Identity: 113/525 - (21%)
• Similarity: 181/525 - (34%)
• Gaps: 182/525 - (34%)

  Fly   236 VDSQDDGLVLP--------SGLSTPA--------------LLQHVQQLR-----GGGIEQPSLLT 273
            :|||.:|.:.|        |||.:|:              .:..::::|     ...:.:.||::
Yeast     1 MDSQVEGKISPSQKESSSTSGLVSPSEDGPAHQKIHRDQLSVDQIKKIREERAQKRQVRRNSLIS 65

  Fly   274 RG-----------FL-KPLL-ADEDVADGLRCLKLNSVSRVCSAPVEGDDIRLLQWNILSQTLGQ 325
            :|           |: :|.| .:.|.:.||       .........:..|::::.:|.|:||| .
Yeast    66 QGKDPDFPTPDLQFIERPFLPINHDNSKGL-------TPATIQVTQDSLDVKIMTYNTLAQTL-I 122

  Fly   326 HNDGFVRCPEE--ALTWEHRKYLIVQEILQNQPDVICLQEVDH--FKFLQTVLGSQNYAGIFFPK 386
            ..|.|   ||.  ||.|..|..::|.|:.:.:|||:.|||||:  ..|.|     :|:..:.|
Yeast   123 RRDFF---PESGPALKWHKRSKVLVHELKKYRPDVVSLQEVDYNELNFWQ-----ENFHKLGF-- 177

  Fly   387 PDSPCLYIEQNNGPDGCAIFYKRDKLQLQG-----YDT----RILEVWRVQSNQVAIAARLRMR- 441
               ..::........|..:.:...|.||..     ||.    .::.. |.::..:|:...|..:
Yeast   178 ---DVIFKRHEGKTHGLLVAWNNKKFQLDNDWMLDYDNILAGNVISA-RTRTKNIALIISLYFKG 238

  Fly   442 ---SSGREFCVATTHLKARHGALLAKLRNE----QGRDLIRFVKQFAGDTPLLLCGDFNAEPVEP 499
               ||.|...||.|||......:..:||..    |....|:...::.|...||: ||||.||.||
Yeast   239 ITDSSSRGIIVANTHLFWHPFGVFERLRQSYLVLQKIQEIKACSKYNGWHSLLM-GDFNTEPEEP 302

  Fly   500 IYATIL------------------------------------GCDLLRLGSAYAD---------V 519
            .|..|.                                    .||....|..::|         .
Yeast   303 PYLAITKRPLILKGPIRAMVECSLAYRYSKKRNGEESDQDDEECDEKSRGEGHSDQPQNPKPESF 367

  Fly   520 KLDREEILHPNADVGEFV-------------------------AKSMKREPPYTTWKIREEGEEC 559
            ...:||    .|.|.:.|                         |.....||..:.|    ....|
Yeast   368 TATKEE----KALVNQLVALHNSLHVKGVSLYGIGYGKVHPENANGSHGEPGLSNW----ANTWC 424

  Fly   560 HTIDYVFYTP-------------------DRLKIKNCLDFPAGEQIGKNRTP-SFQYPSDHFSLV 604
            ..:||:||..                   :.:||...|..|..:::.|:..| ..:|.|||.||:
Yeast   425 GLLDYIFYIEGDHNQDTRQKEPLNAFEGNNNVKIIGYLRMPCAQEMPKHSQPFEGEYASDHISLM 489

  Fly   605 CDFEL 609
            |...|
Yeast   490 CQIRL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	92/407 (23%)
NGL3	NP_013588.1	CCR4	67..496	CDD:227564	101/459 (22%)