DRSC/TRiP Functional Genomics Resources

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Protein Alignment cu and cnot6l

DIOPT Version :9

Sequence 1:NP_001097746.1 Gene:cu / 41339 FlyBaseID:FBgn0261808 Length:642 Species:Drosophila melanogaster
Sequence 2:NP_001018474.1 Gene:cnot6l / 553665 ZFINID:ZDB-GENE-050522-302 Length:559 Species:Danio rerio


Alignment Length:364 Identity:86/364 - (23%)
Similarity:134/364 - (36%) Gaps:106/364 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   333 CPEEALTWEHRKYLIVQEILQNQPDVICLQEVD---HFKFLQTVLGSQNYAGIFFPKPDSPCLYI 394
            ||..||.||:||..|::||.....|:|.||||:   ::.|....|..:.|.|.|.||..:..:..
Zfish   205 CPSWALNWEYRKKGIMEEITNCDADIISLQEVETEQYYTFFLETLKDRGYDGFFCPKSRAKLVSE 269

  Fly   395 EQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLRMRSSGREFCVATTHLKARHG 459
            ::....|||.:|:|.:|..|       ::...|:.||||:|     .|.|.|..:.....|...|
Zfish   270 QERKHVDGCGVFFKTEKFAL-------VQKHTVEFNQVAMA-----NSEGSEVMLNRVMTKDNIG 322

  Fly   460 -ALLAKLRNE----------------------------------QGRDLIRFVKQFA-------- 481
             |:|.:::.:                                  |....:..:|..|        
Zfish   323 VAVLLEVKEDLFAAGLKPPPEKQLLLVANAHMHWDPEYSDVKLIQTMMFLSELKSIAERASGSIN 387

  Fly   482 --------GDTPLLLCGDFNAEPVEPIYATILGCDLLRLGSAYADVKLDREEILHPNADVGEFVA 538
                    ...|::||.|.|:.|...:      .:.|..|.. |:...|.:|:.:.:. :..|..
Zfish   388 SSSPTSETSSIPIVLCADLNSLPDSGV------VEYLSNGGV-AENHKDFKELRYSDC-LTNFSC 444

  Fly   539 KSMKREP-------------------PYTTWKIREEGEECHTIDYVFYTPDRLKIKNCLDFPAGE 584
            .....:|                   |||.:....:|    .|||:|::...:.:...|. |...
Zfish   445 NGKNGKPDGSITHSFQLKSAYEGNLMPYTNYTYDFKG----VIDYIFFSKTHMSVLGVLG-PLET 504

  Fly   585 QIGKNRT----PSFQYPSDHFSLVCDFEL---LPPTENG 616
            |..|:..    |....|||||||:...|.   |||. ||
Zfish   505 QWLKDNNITGCPHPHIPSDHFSLLAQLEYHHPLPPL-NG 542

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cuNP_001097746.1 EEP 312..609 CDD:382041 80/352 (23%)
cnot6lNP_001018474.1 Nuclease domain. /evidence=ECO:0000250 1..550 86/364 (24%)
Required for interaction with cnot1, cnot3 and cnot7. /evidence=ECO:0000250 1..148
leucine-rich repeat 32..52 CDD:275378
LRR_8 51..107 CDD:290566
LRR_4 51..91 CDD:289563
leucine-rich repeat 53..75 CDD:275378
leucine-rich repeat 76..98 CDD:275378
leucine-rich repeat 99..121 CDD:275378
leucine-rich repeat 122..133 CDD:275378
Deadenylase_CCR4b 186..533 CDD:197339 80/352 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5239
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D724242at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

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