Protein Alignment cu and Angel1

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_017449718.1
• Gene: Angel1 / 362765
• RGDID: 1306238
• Length: 690
• Species: Rattus norvegicus
• Alignment Length: 721
• Identity: 152/721 - (21%)
• Similarity: 236/721 - (32%)
• Gaps: 290/721 - (40%)

  Fly    77 PNHHEDDGKLAGERHREIPCSNCLKTA-PGHLIDRQSAINEMCQRLCGPECRRPQGLTLDGVRQD 140
            |:..|.:|.|  ::.||...:..|.|| .|.|.|:..|.:.:             .|.:|
  Rat    75 PDQEECEGLL--QQWREEGWNQTLSTASEGPLADKGLAESSL-------------ALLMD----- 119

  Fly   141 FLRQYEIAEAVAKTSAMTSTVQMKQRLAARKLE-------FEKEMEMDE-QLGVASPRNDINLG- 196
                 ...|....:....|:.|:....||..|:       .|:.:..|| .|..|.|   :..|
  Rat   120 -----NSGEQDTASEDKWSSRQLSDLRAADNLDQPFPEVLGEEPLAEDEGPLWAAVP---VQTGP 176

  Fly   197 QSSTVAATGMG-----EFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGLVLPSGLSTPALLQ 256
            |.:..|...||     ::|.:|         .|.:::.||:           .:|...::....:
  Rat   177 QYADCAVLPMGAMAAEQWEEDP---------AMVAWSIAPE-----------PMPQEETSMWPFE 221

  Fly   257 HVQQLRGGGIEQP--SLLTRGFLKPLLADEDV-----ADGLRCLKLNSVSRVCSAPVEGD----D 310
            .::||:...:|.|  .:|.|.:       ||.     |.||..               ||    .
  Rat   222 GLEQLQPPPMEIPYHEILWREW-------EDFSTQPDAQGLEA---------------GDGPQFQ 264

  Fly   311 IRLLQWNILSQTL-GQHNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEV--DHF-KFLQ 371
            ..|:.:|||:|.| .|.::.::.|..:.|.|.:|...::||.....||::|||||  ||: :.|:
  Rat   265 FTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLE 329

  Fly   372 TVLGSQNYAGIFFPKPDSPCLYIEQNNG--PDGCAIFYK---------------RDKLQLQGYDT 419
            ..|....:.          |.| ::..|  .||||:.||               |..|:|...|.
  Rat   330 PSLRMMGFT----------CFY-KRRTGCKTDGCAVCYKPTRFRLLCASPVEYFRPGLELLNRDN 383

  Fly   420 RILEVWRVQS------NQVAIAARLRMRSSGREFCVATTHL----------KARHGALLAKLRNE 468
            ..| |..:|.      .||::|          ..|||.||:          .|:...|||::
  Rat   384 VGL-VLLLQPLVPEGLGQVSVA----------PLCVANTHVLYNPRRGDVKLAQMAILLAEV--- 434

  Fly   469 QGRDLIRFVKQFAGDTPLLLCGDFNAEPVEPIYATI----------------------------- 504
               |.:..:.. ....|::||||.|:.|..|:|..|
  Rat   435 ---DKVARLSD-GSHCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRK 495

  Fly   505 ---------LG-------------------------------CDL-------LRLGSAYADVKLD 522
                     ||                               |||       |.|.....|.|.|
  Rat   496 LQAPLWPSSLGITDCCQYVTSCHPKRSERLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPD 560

  Fly   523 R----------EEI-----------------LHPNADVGEFVAKSMKREPPYTTWKIREEGEECH 560
            |          |||                 ||..:....|:.:..:  |..||..:...    .
  Rat   561 RPAGWAECIFEEEISELEPVFPRTIGTIQHCLHLTSVYTHFLPQHGR--PEVTTMPLGLG----M 619

  Fly   561 TIDYVFYTPDRLKIKNCLDFP---------------AGEQI--GKNRTPSFQYPSDHFSLVCDF- 607
            |:||:|::.:..:.:|..|..               ..|:|  ..|..|:..|.|||..|:..|
  Rat   620 TVDYIFFSAESCENENRSDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFG 684

  Fly   608 -ELLPP 612
             |:..|
  Rat   685 MEVTAP 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	99/455 (22%)
Angel1	XP_017449718.1	EEP	268..683	CDD:469791	97/449 (22%)