DRSC/TRiP Functional Genomics Resources

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Protein Alignment cu and cnot6a

DIOPT Version :9

Sequence 1:NP_001097746.1 Gene:cu / 41339 FlyBaseID:FBgn0261808 Length:642 Species:Drosophila melanogaster
Sequence 2:NP_997825.1 Gene:cnot6a / 324048 ZFINID:ZDB-GENE-030131-2768 Length:557 Species:Danio rerio


Alignment Length:497 Identity:131/497 - (26%)
Similarity:185/497 - (37%) Gaps:137/497 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   229 SAPKINNVDSQDDGLVLPSGLSTPALLQHVQQLRGGGIEQPSLL---TRGFLKPLLADE-----D 285
            |:.||.::.::     |.:.::...||.:..|||....|...|.   |.|.....||.|     .
Zfish    82 SSNKIRSLPAE-----LGNMINLRELLLNNNQLRVLPFELGKLFQLQTLGLKGNPLAQEILNLYQ 141

  Fly   286 VADGLRCL---KLNSVSRVCSAPVEGDDIR------------------LLQWNILSQTLGQHN-D 328
            ..||.|.|   .|::::....||:|....|                  ::.:|:|........ .
Zfish   142 EPDGTRRLLNYLLDNLAGTKRAPIEQPPPRSWIPLQEPDRTRPAALFSVMCYNVLCDKYATRQLY 206

  Fly   329 GFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVD---HFKFLQTVLGSQNYAGIFFPKPDSP 390
            |:  ||..||.||:||..|:||||....|:|.||||:   ::.:....|..|.|.|.|.||..:.
Zfish   207 GY--CPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLLELKEQGYEGFFSPKSRAR 269

  Fly   391 CLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLRMRSSGREFCVATTHLK 455
            .:........||||:|||.||..|       ::...|:.||:|:|     .|.|.|..:.....|
Zfish   270 TMSESDRKHVDGCAVFYKTDKFSL-------VQKHTVEFNQLAMA-----NSEGSEAMLNRVMTK 322

  Fly   456 ARHG-ALLAKLRNEQ-----GRDLIRFVKQF---------------------------------- 480
            ...| |:|.:||.|.     |:.|....||.                                  
Zfish   323 DNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSDVKLVQTMMFLSEVKNIVD 387

  Fly   481 -----------AGDT---PLLLCGDFNAEPVEPI--YATILGCDLLRLGSAYADVK----LDREE 525
                       :|:|   ||:||.|.|:.|...:  |.:..|.|     .|:.|.|    :|...
Zfish   388 KATRSLKLSSVSGETNAIPLVLCADLNSLPDSGVVEYLSTGGVD-----GAHKDFKELRYIDSLT 447

  Fly   526 ILHPNADVGE--------FVAKSMKRE--PPYTTWKIREEGEECHTIDYVFYTPDRLKIKNCLDF 580
            ..:.|...|.        |..||....  .|||.:....:|    .|||:||:...|.:...|..
Zfish   448 NFNCNGKNGTSSTRITHGFKLKSAYENGLMPYTNYTFDFKG----IIDYIFYSQPLLNVLGVLGP 508

  Fly   581 PAGEQIGKNRT---PSFQYPSDHFSLVCDFELL---PPTENG 616
            .....:.:|..   |....|||||||....|||   ||..||
Zfish   509 LEHHWLLENNVTGCPHPHIPSDHFSLFAQLELLLPFPPAVNG 550

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cuNP_001097746.1 EEP 312..609 CDD:382041 100/391 (26%)
cnot6aNP_997825.1 LRR_8 51..132 CDD:290566 13/54 (24%)
LRR_4 51..91 CDD:289563 3/8 (38%)
leucine-rich repeat 53..75 CDD:275378
leucine-rich repeat 76..90 CDD:275378 3/7 (43%)
EEP 190..540 CDD:294334 99/372 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5239
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D724242at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.820

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