Protein Alignment cu and cnot6a

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: XP_068071884.1
• Gene: cnot6a / 324048
• ZFINID: ZDB-GENE-030131-2768
• Length: 572
• Species: Danio rerio
• Alignment Length: 580
• Identity: 144/580 - (24%)
• Similarity: 206/580 - (35%)
• Gaps: 185/580 - (31%)

  Fly   199 STVAATGMGEFEFEPPRDLLLYLV---------------------RMGSFNSA------------ 230
            :|...|||.:.:::||....:|.:                     ::.|.:||
Zfish     9 ATCLITGMPKEKYDPPDPRRMYTIMSSEEAANGKKSTWAELEIVGKVKSLSSALWSLTHLTALYI 73

  Fly   231 ------------PKINN---VDSQDDGL-VLPSGL----STPALLQHVQQLRGGGIEQPSLL--- 272
                        .|:||   :|...:.: .||:.|    :...||.:..|||....|...|.
Zfish    74 SDNSLSRIPPDIAKLNNLVYLDLSSNKIRSLPAELGNMINLRELLLNNNQLRVLPFELGKLFQLQ 138

  Fly   273 TRGFLKPLLADE-----DVADGLRCL---KLNSVSRVCSAPVEGDDIR----------------- 312
            |.|.....||.|     ...||.|.|   .|::::....||:|....|
Zfish   139 TLGLKGNPLAQEILNLYQEPDGTRRLLNYLLDNLAGTKRAPIEQPPPRSWIPLQEPDRTRPAALF 203

  Fly   313 -LLQWNILSQTLGQHN-DGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVD---HFKFLQT 372
             ::.:|:|........ .|:  ||..||.||:||..|:||||....|:|.||||:   ::.:...
Zfish   204 SVMCYNVLCDKYATRQLYGY--CPSWALNWEYRKKSIMQEILSCSADIISLQEVETEQYYNYFLL 266

  Fly   373 VLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAAR 437
            .|..|.|.|.|.||..:..:........||||:|||.||..|       ::...|:.||:|:|
Zfish   267 ELKEQGYEGFFSPKSRARTMSESDRKHVDGCAVFYKTDKFSL-------VQKHTVEFNQLAMA-- 322

  Fly   438 LRMRSSGREFCVATTHLKARHG-ALLAKLRNEQ-----GRDLIRFVKQF---------------- 480
               .|.|.|..:.....|...| |:|.:||.|.     |:.|....||.
Zfish   323 ---NSEGSEAMLNRVMTKDNIGVAVLLELRKEMMELSAGKPLHGMEKQLLLVANAHMHWDPEYSD 384

  Fly   481 -----------------------------AGDT---PLLLCGDFNAEPVEPI--YATILGCDLLR 511
                                         :|:|   ||:||.|.|:.|...:  |.:..|.|
Zfish   385 VKLVQTMMFLSEVKNIVDKATRSLKLSSVSGETNAIPLVLCADLNSLPDSGVVEYLSTGGVD--- 446

  Fly   512 LGSAYADVK----LDREEILHPNADVGE--------FVAKSMKRE--PPYTTWKIREEGEECHTI 562
              .|:.|.|    :|.....:.|...|.        |..||....  .|||.:....:|    .|
Zfish   447 --GAHKDFKELRYIDSLTNFNCNGKNGTSSTRITHGFKLKSAYENGLMPYTNYTFDFKG----II 505

  Fly   563 DYVFYTPDRLKIKNCLDFPAGEQIGKNRT---PSFQYPSDHFSLVCDFELL---PPTENG 616
            ||:||:...|.:...|.......:.:|..   |....|||||||....|||   ||..||
Zfish   506 DYIFYSQPLLNVLGVLGPLEHHWLLENNVTGCPHPHIPSDHFSLFAQLELLLPFPPAVNG 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	100/391 (26%)
cnot6a	XP_068071884.1	LRR	<54..>147	CDD:443914	19/92 (21%)
		leucine-rich repeat	68..90	CDD:275378	1/21 (5%)
		leucine-rich repeat	91..105	CDD:275378	1/13 (8%)
		EEP	205..555	CDD:469791	99/372 (27%)