Protein Alignment cu and Noct

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_612535.1
• Gene: Noct / 310395
• RGDID: 1587344
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 430
• Identity: 174/430 - (40%)
• Similarity: 229/430 - (53%)
• Gaps: 56/430 - (13%)

  Fly   196 GQSSTVAATGMGEFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGL-----VLPSGLSTPALL 255
            |...|:|...:|.....|.    |.....|:..|.|:  .|....:|.     .|...:::.|..
  Rat    27 GPRRTLAPPVLGSRPASPQ----LQAAASGAARSRPR--TVSPMGNGTSRLYSALAKTINSSAAA 85

  Fly   256 QHVQQLRGGG------IEQPSLL--TRGFL--KPLLADEDVADGLRCLKLNSVSRVCSAPVEGDD 310
            ||.:.|....      |:...||  .|..|  :|.....|..|    |:.:     ||:  ....
  Rat    86 QHPEYLVSADPEHLEPIDPKELLEECRAVLHTRPPRYQRDFVD----LRTD-----CSS--SHPP 139

  Fly   311 IRLLQWNILSQTLGQHNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVDH-FKFLQTVL 374
            ||::|||||:|.||:..|.||:||.|||.||.||.||::|||..|||::||||||| |...|.:|
  Rat   140 IRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLL 204

  Fly   375 GSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLR 439
            ....|.|.|||||.||||.:|.||||||||:|:.:.:.:|.......|....:::||||||..|.
  Rat   205 SRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQSRFKLINSTNIRLTAMTLKTNQVAIAQTLE 269

  Fly   440 MRSSGREFCVATTHLKARHGALLAKLRNEQGRDLIRFVKQF--AGDTPLLLCGDFNAEPVEPIYA 502
            .:.|||:||:|.||||||.|  ..:.|:.||.||::.::..  ....||::||||||||.|.:|.
  Rat   270 CKESGRQFCIAVTHLKARTG--WERFRSAQGCDLLQNLQNITEGAKIPLIVCGDFNAEPTEEVYK 332

  Fly   503 TILGCDLLRLGSAYADVKLDREEILHPNADVGEFVAKSMKREPPYTTWKIREEGEECHTIDYVFY 567
            ...... |.|.|||        ::|.|:.          :.||||||||||..||..||:||::|
  Rat   333 HFASSS-LNLNSAY--------KLLSPDG----------QSEPPYTTWKIRTSGECRHTLDYIWY 378

  Fly   568 TPDRLKIKNCLDFPAGEQIGKNRTPSFQYPSDHFSLVCDF 607
            :...|.:.:.||....||||.||.|||.|||||.||||||
  Rat   379 SRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDF 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	146/299 (49%)
Noct	NP_612535.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..66		10/44 (23%)
		Deadenylase_nocturnin	141..420	CDD:197330	146/299 (49%)
		Interaction with PPARG. /evidence=ECO:0000250|UniProtKB:O35710	340..350		5/17 (29%)