DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cu and Angel2

DIOPT Version :9

Sequence 1:	NP_001097746.1	Gene:	cu / 41339	FlyBaseID:	FBgn0261808	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	XP_038946747.1	Gene:	Angel2 / 305035	RGDID:	1305056	Length:	544	Species:	Rattus norvegicus

Alignment Length:	485	Identity:	114/485 - (23%)
Similarity:	170/485 - (35%)	Gaps:	160/485 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   246 PSGLSTPALLQHVQQLRGGGIEQPSLLTR---GFLKPLLADEDVADGLRCLKLNSVSRVCSAPVE 307
            |..||..:|....:.:.....::||...|   |.:|                 .|...:||...|
  Rat    97 PDQLSNTSLFHLSRYVMNSDRDEPSSKRRKHQGTIK-----------------RSWEYLCSHNKE 144

  Fly   308 ---------GD----------DIRLLQWNILSQTLGQHNDGFVR-CPEEALTWEHRKYLIVQEIL 352
                     ||          |..::.:|||||.|.:.|....| |....|.|..|...|::||.
  Rat   145 KTKDLEDRNGDSTCEDCEDKFDFSVMSYNILSQELLEDNSHLYRHCRRPVLHWSFRFPNILKEIK 209

  Fly   353 QNQPDVICLQEV--DHF-KFLQTVLGSQNYAGIFFPKPDSPCLY-IEQNNGPDGCAIFYKRDKLQ 413
            ....||:|||||  ||: ..::..|.|..|          .|.| ::....||||||.:|..|..
  Rat   210 HFDADVLCLQEVQEDHYGTEIRPSLESLGY----------HCEYKMKTGRKPDGCAICFKHSKFS 264

  Fly   414 LQGYDTRILEVWR-----VQSNQVAIAARLR---MRSSGREFCVATTHL--KARHG--------A 460
            |...:.  :|..|     :..:.:.:...|:   .|::....|:|.|||  ..|.|        .
  Rat   265 LLSVNP--VEFCRRDIPLLDRDNIGLVLLLQPKIPRAASPSICIANTHLLYNPRRGDIKLTQLAM 327

  Fly   461 LLAKLRNEQGRDLIRFVKQFAGD-TPLLLCGDFNAEPVEPIYATI----LGCDLLRLGSAYADVK 520
            |||::.|        ...|..|. .|:::|||||:.|..|:|:.|    |..:.|.:|......:
  Rat   328 LLAEISN--------VAHQKDGSFCPIVMCGDFNSVPGSPLYSFIKEGKLNYEGLAIGKVSGQEQ 384

  Fly   521 LDREE------ILHPN---------------------ADVGEFVAKSMKREPPYTTWKIRE---- 554
            ..|.:      |..||                     :||.:  |:..|.|.|....|:..
  Rat   385 SSRGQRILSIPIWPPNLGISQNCVYEAQQVPKVEKTDSDVTQ--AQQEKAEVPVPADKVSSHLQH 447

  Fly   555 ------------------EGEECH-----TIDYVFYTPDR----------------LKIKNCLDF 580
                              |...||     |:||:||:.::                ||:...|..
  Rat   448 GFSLSSVYSHYVPDTGVPEVTTCHSRSAITVDYIFYSAEKDDTARGPGAEVALVGGLKLLARLSL 512

  Fly   581 PAGEQIGK-NRTPSFQYPSDHFSLVCDFEL 609
            ...:.:.. |..|:....|||..|:..|.|
  Rat   513 LTEQDLWTVNGLPNEHNSSDHLPLLAKFRL 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:382041	97/395 (25%)
Angel2	XP_038946747.1	EEP	169..542	CDD:412407	97/394 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5239
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D724242at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820