DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cu and Zfp503

DIOPT Version :9

Sequence 1:	NP_001097746.1	Gene:	cu / 41339	FlyBaseID:	FBgn0261808	Length:	642	Species:	Drosophila melanogaster
Sequence 2:	NP_663434.2	Gene:	Zfp503 / 218820	MGIID:	1353644	Length:	652	Species:	Mus musculus

Alignment Length:	267	Identity:	54/267 - (20%)
Similarity:	80/267 - (29%)	Gaps:	63/267 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GLRENYGHRRQPALGKAMPVTALLLNLESNPLDYSRNDIGAELLEDDDKPPQLFSVTDEPPSPNE 71
            |:....||.|....|.        :|::.|  .:|....|.:.|..|.......|....|.:|..
Mouse   280 GVPAGLGHGRISCGGG--------INVDVN--QHSEGGPGGKALGSDCGGSSSSSSGSGPSAPTS 334

  Fly    72 ED------------YK--------PPNHHEDDGKLAGE----RHREIPCSNCL-KTAPGHLIDRQ 111
            ..            ||        ||......|.|||.    ..:.:|....| .|.||.|:..|
Mouse   335 SSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQ 399

  Fly   112 SAINEM----CQRLCGPE----CRRPQGLTLDGVRQDFLRQYEIAEAVAKTSAMTSTVQMKQRLA 168
            .|....    |.:..|..    ...|..:|....|..:...|..|..:|..:|.:::.......|
Mouse   400 LAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAA 464

  Fly   169 ARKLEFEKEMEMDEQLGVASPRNDINLGQSSTVAATGMG------------EFEFEPPRDLLLYL 221
            |..|:        ....:..|.:.::...||..||...|            .:.|..|.|.|.::
Mouse   465 AAALK--------SGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHI 521

  Fly   222 VRMGSFN 228
            ....|.|
Mouse   522 CNWVSAN 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:382041
Zfp503	NP_663434.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..72
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	126..283		1/2 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..338		9/43 (21%)
		nlz1	361..421	CDD:338339	14/59 (24%)
		C2H2 Zn finger	522..548	CDD:275368	2/7 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S8132
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950