Protein Alignment cu and angl-1

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_001303707.1
• Gene: angl-1 / 189127
• WormBaseID: WBGene00020955
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 121/565 - (21%)
• Similarity: 179/565 - (31%)
• Gaps: 199/565 - (35%)

  Fly    12 YGHRRQPALGKAMPVTALLLNLESNPLDYSRNDIGAELLEDDD---------------KPPQLFS 61
            :||||..                    .|:.|    :.|.|||               ||.:...
 Worm    39 HGHRRSS--------------------QYTWN----KFLADDDAANQQLPAPMYRPPPKPIKTIR 79

  Fly    62 VTDEPPSPNEEDYKPPNHHEDDGKLAGERHREIPCSNCLKTAPGHLIDRQSAINEMCQRLCGPEC 126
            :.|:..:|.... .||:.|                      ||.. :|:|..........|
 Worm    80 LGDDEATPGSSS-SPPSLH----------------------APSS-VDQQQQQPTTSSNFC---- 116

  Fly   127 RRPQGLTLDGVRQDFLRQYEIAEAVAKTSAMTSTVQMKQRLAARKLEFEKEMEMDEQLGVASPRN 191
                                 |..:||...:|.|         :|:|   |:.:||:     |..
 Worm   117 ---------------------ASWLAKNQHLTRT---------KKVE---EVVLDER-----PTG 143

  Fly   192 DINLGQSSTVAATGMGEFE-----FEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGLVLPS---- 247
                .|..::.......||     ...||||...:  .|.......:..:||| ||:|...
 Worm   144 ----SQDDSIIVLDDDIFEKTRKKSSEPRDLKKKV--FGRQEPGTTVGRIDSQ-DGIVFVGEYPR 201

  Fly   248 -GLSTPALLQHVQQL---RGGGIEQPS----------LLTRGFLKPLLADEDVADGLRCLKLNSV 298
             |.:...|..::.:.   .|.....||          .:..||.:..   :|....:||......
 Worm   202 RGRTMTQLETNMAETFWSNGASSSSPSSTGTTQQTFKKINDGFSRDC---KDFKRLVRCWNRTEA 263

  Fly   299 SRVCSAPVEGDDIRLLQWNILSQT-------LGQHNDGFVRCPEEALTWEHRKYLIVQEILQNQP 356
            ......|.......:..:|:|.|.       |.:|..|    ..:.|.||||...:..|:.....
 Worm   264 QSRSKIPKISSKFTICSYNVLCQKTIARTDYLYRHLQG----SAQFLDWEHRWRGLQVELPTFDA 324

  Fly   357 DVICLQEV--DHF-KFLQTVLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQG-- 416
            |::.||||  ||| :..|.::....|.|::..|     ...:|.:  ||||:||...|.:|..
 Worm   325 DILGLQEVQADHFVEHFQPLMKKYGYEGVYKQK-----FGTQQKD--DGCALFYHPAKFELVANQ 382

  Fly   417 ------YDTRILEVWRVQSNQVAIA--ARLRMRSSGREFCVATTHLKARHGALLAKLRNEQGRD- 472
                  .||.|       ||:..||  ..||.|.:.....||.|||          |.||:..|
 Worm   383 EVNYFISDTAI-------SNRENIAQIVALRCRITKELILVANTHL----------LFNEERGDV 430

  Fly   473 -------LIRFVKQFAGD-----TPLLLCGDFNAEPVEPIYATIL 505
                   |...:.:...|     .|:.:.||||.||...:|..|:
 Worm   431 KLAQLAILFASIHKMREDFAPMVPPVFVMGDFNIEPNSKVYDFIV 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	63/227 (28%)
angl-1	NP_001303707.1	EEP	280..>478	CDD:469791	63/224 (28%)