Protein Alignment cu and pde-12

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_499388.1
• Gene: pde-12 / 176514
• WormBaseID: WBGene00011268
• Length: 628
• Species: Caenorhabditis elegans
• Alignment Length: 509
• Identity: 106/509 - (20%)
• Similarity: 180/509 - (35%)
• Gaps: 157/509 - (30%)

  Fly   175 EKEMEMDEQLGVASPRNDINLGQSSTVAATGMGEFEFEPPRDLLLYLVRMG-SFNSAPKINNVDS 238
            :||....|:||.....||     |..:|      ||.|..|...|:    | ||..:......|.
 Worm   203 QKETGKSEKLGPTQKDND-----SLKLA------FEDEAARTFKLH----GYSFRHSGPYFQPDE 252

  Fly   239 QD----DGLVLPSGLSTPALL----QHVQQLRGGGIEQPSLLTRGFLKPLLADEDVADGLRCLKL 295
            :|    ..:|:.||...||..    :.:.||.               ..::.||.|
 Worm   253 KDVSRLVAVVVESGKDHPAYAAISSRPISQLH---------------DEVITDEQV--------- 293

  Fly   296 NSVSRVCSAPVEGDD--IRLLQWNILSQ-----TLGQHNDGFVRCPEEALTWEHRKYLIVQE--- 350
                :.|......||  ||::.:|||:.     ||.|....|..|.:.:....:|..:.:::
 Worm   294 ----KWCEEISLEDDSTIRIMSYNILADLYLNLTLPQEQLFFNYCQKSSQRIIYRTPIFLKQLHD 354

  Fly   351 -ILQNQPDVICLQEVD---HFKFLQTVLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDK 411
             |...:..:|.|||||   |..|:...|.:.:|:.....|..:.         .:|.||.:...:
 Worm   355 FIHSARCSLIFLQEVDLSRHENFIVPFLNTISYSSEIAKKVGTV---------SEGVAIIFDSQR 410

  Fly   412 LQL------------QGYDTRILEV---------WRVQSNQVAIAARLRMRSSGREFCVATTHLK 455
            .|:            .|....|||.         .|....|:.:   |:...:|:......|||.
 Worm   411 FQVISSKCYGVAELASGDILGILETSEESKERFSTRPTVLQIVV---LKDSRTGKLLVCGNTHLH 472

  Fly   456 ----ARHGALLAKLR--------NEQGRDLIRFVKQFAGDTPLLLCGDFNAEPVEPIYATILGCD 508
                ..|..:|..|.        .|:.|:|.:.:     :..:|..||||:.|...::      :
 Worm   473 HNPIDEHVKVLQALTCTRKLLEIYEETRELNKGI-----EVLVLFGGDFNSTPNGAVF------N 526

  Fly   509 LLRLGS--------------AYADVKLDREEILHPNADVGEFVAKSMKREPPYTTWKIREEGE-- 557
            |:.:|:              ...|:|:|::             ...:...|.||.:....:.:
 Worm   527 LMSMGNLPKEDAVWNCDSKITPQDIKIDKK-------------MDCLTGTPEYTNYTASSQKDGF 578

  Fly   558 -ECHTIDYVFYTPDRLKIKNCLDFPAGEQIGK-NRTPSFQYPSDHFSLVCDFEL 609
             .|  :||: :......|::| ..|:.|::.| ...||...||||..::||.::
 Worm   579 VGC--LDYI-WGVGATSIRHC-PLPSHEKVIKYTALPSPISPSDHLPIICDIKI 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	73/359 (20%)
pde-12	NP_499388.1	EEP	309..628	CDD:469791	72/358 (20%)