Protein Alignment cu and Noct

DIOPT Version :10

• Sequence 1: NP_001097746.1
• Gene: cu / 41339
• FlyBaseID: FBgn0261808
• Length: 642
• Species: Drosophila melanogaster
• Sequence 2: NP_033964.1
• Gene: Noct / 12457
• MGIID: 109382
• Length: 429
• Species: Mus musculus
• Alignment Length: 430
• Identity: 175/430 - (40%)
• Similarity: 231/430 - (53%)
• Gaps: 55/430 - (12%)

  Fly   196 GQSSTVAATGMGEFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGL-----VLPSGLSTPALL 255
            |...|:|...:|.   .|....|......|:..|.|:  .|.|..:|.     .|...:::.|..
Mouse    27 GPRRTLAPPVLGS---RPKSPQLQAAAASGAARSRPR--TVSSMGNGTSRLYSALAKTVNSSAAA 86

  Fly   256 QHVQQLRGGG------IEQPSLL--TRGFL--KPLLADEDVADGLRCLKLNSVSRVCSAPVEGDD 310
            ||.:.|....      |:...||  .|..|  :|.....|..|    |:.:     ||:  ....
Mouse    87 QHPEYLVSTDPEHLEPIDPKELLEECRAVLHTRPPRYQRDFVD----LRTD-----CSS--SHSP 140

  Fly   311 IRLLQWNILSQTLGQHNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVDH-FKFLQTVL 374
            ||::|||||:|.||:..|.||:||.|||.||.||.||::|||..|||::||||||| |...|.:|
Mouse   141 IRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLL 205

  Fly   375 GSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLR 439
            ....|.|.|||||.||||.:|.||||||||:|:.:::.:|.......|....:::||||||..|.
Mouse   206 SRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQNRFKLISSTNIRLTAMTLKTNQVAIAQTLE 270

  Fly   440 MRSSGREFCVATTHLKARHGALLAKLRNEQGRDLIRFVKQF--AGDTPLLLCGDFNAEPVEPIYA 502
            .:.|||:||:|.||||||.|  ..:.|:.||.||::.::..  ....||::||||||||.|.:|.
Mouse   271 CKESGRQFCIAVTHLKARTG--WERFRSAQGCDLLQNLQNITQGAKIPLIVCGDFNAEPTEEVYK 333

  Fly   503 TILGCDLLRLGSAYADVKLDREEILHPNADVGEFVAKSMKREPPYTTWKIREEGEECHTIDYVFY 567
            ...... |.|.|||        ::|.|:.          :.||||||||||..||..||:||::|
Mouse   334 HFASSS-LNLNSAY--------KLLSPDG----------QSEPPYTTWKIRTSGECRHTLDYIWY 379

  Fly   568 TPDRLKIKNCLDFPAGEQIGKNRTPSFQYPSDHFSLVCDF 607
            :...|.:.:.||....||||.||.|||.|||||.||||||
Mouse   380 SRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDF 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cu	NP_001097746.1	EEP	312..609	CDD:469791	146/299 (49%)
Noct	NP_033964.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	21..68		11/45 (24%)
		Deadenylase_nocturnin	142..421	CDD:197330	146/299 (49%)
		Interaction with PPARG. /evidence=ECO:0000269|PubMed:20498072	341..351		5/17 (29%)