DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35A1 and UGT85A1

DIOPT Version :9

Sequence 1:	NP_524314.2	Gene:	Ugt35A1 / 41334	FlyBaseID:	FBgn0026315	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_173656.1	Gene:	UGT85A1 / 838846	AraportID:	AT1G22400	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	540	Identity:	115/540 - (21%)
Similarity:	191/540 - (35%)	Gaps:	180/540 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTF----------GSDKNE--PNFRVIG 82
            |...::.| |:|.:.......:..|.|..||..||.:||.          ||:..:  |:||
plant    10 QKPHVVCV-PYPAQGHINPMMRVAKLLHARGFYVTFVNTVYNHNRFLRSRGSNALDGLPSFR--- 70

  Fly    83 AKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDD--AAVKDLL---NSGE------ 136
               ...|.......|..           .||.:..|..|.:.:  |..::||   |:|:
plant    71 ---FESIADGLPETDMD-----------ATQDITALCESTMKNCLAPFRELLQRINAGDNVPPVS 121

  Fly   137 --------KFDLVIMEAVQT-EALFGLIQ--------HF------GAETIGISSYGTDTHIDELM 178
                    .|.|.:.|.:.. |.||....        ||      |...:...||.|..::::.:
plant   122 CIVSDGCMSFTLDVAEELGVPEVLFWTTSGCAFLAYLHFYLFIEKGLCPLKDESYLTKEYLEDTV 186

  Fly   179 GNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSL--D 241
                               :||                     :|:.:::..|..|:..::.  |
plant   187 -------------------IDF---------------------IPTMKNVKLKDIPSFIRTTNPD 211

  Fly   242 EVLDSFAL-----------MLLG-----QHFSLSYPRPYLPNMIEVGGLHLQQKRKVQP------ 284
            :|:.||||           ::|.     :|..:...:..||.:..||.|||...|:::.
plant   212 DVMISFALRETERAKRASAIILNTFDDLEHDVVHAMQSILPPVYSVGPLHLLANREIEEGSEIGM 276

  Fly   285 ----LAKELSEFVE----QSEKGVIYFSMGSNIKSKDLPPSTRKMLMQ---TFASVPQRVLWKFE 338
                |.||..|.::    :::..|||.:.||      :...:.|.|::   ..|...:..||...
plant   277 MSSNLWKEEMECLDWLDTKTQNSVIYINFGS------ITVLSVKQLVEFAWGLAGSGKEFLWVIR 335

  Fly   339 DDQ------------LPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGL 391
            .|.            |.|..|...::.|.||..:|:||.:..|:||.|..|.:||:..|.|::..
plant   336 PDLVAGEEAMVPPDFLMETKDRSMLASWCPQEKVLSHPAIGGFLTHCGWNSILESLSCGVPMVCW 400

  Fly   392 PIFYDQHLNVQ---RAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKET 453
            |.|.||.:|.:   ....||..:..|   |...|:..:::||:..        .|.|..|
plant   401 PFFADQQMNCKFCCDEWDVGIEIGGD---VKREEVEAVVRELMDG--------EKGKKMR----- 449

  Fly   454 ALERAIWWTEYVLRHKGAKH 473
              |:|:.|..  |..|..:|
plant   450 --EKAVEWQR--LAEKATEH 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	115/540 (21%)
Ugt35A1	NP_524314.2	UDPGT	55..526	CDD:278624	110/515 (21%)
UGT85A1	NP_173656.1	Glycosyltransferase_GTB_type	14..453	CDD:299143	109/520 (21%)
UGT85A1	NP_173656.1	MGT	20..454	CDD:273616	108/514 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050