DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35A1 and UGT85A3

DIOPT Version :9

Sequence 1:	NP_524314.2	Gene:	Ugt35A1 / 41334	FlyBaseID:	FBgn0026315	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_173655.2	Gene:	UGT85A3 / 838845	AraportID:	AT1G22380	Length:	488	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	115/541 - (21%)
Similarity:	201/541 - (37%)	Gaps:	150/541 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 FAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTF----------GSDKNE 75
            |.:|.    |...::.| |:|.:.......:..|.|..:|.:||.:||.          |::..:
plant     5 FVSNE----QKPHVVCV-PYPAQGHINPMMKVAKLLHVKGFHVTFVNTVYNHNRLLRSRGANALD 64

  Fly    76 --PNFRVIGAKKIHEIMAAFGNADYTQ---TASQWQMLTMTTQFLNLLTTSIL--DDAAVKDLLN 133
              |:|:.   :.|.:.:...| .|.||   ..|:.........|..||...:.  |...|..:::
plant    65 GLPSFQF---ESIPDGLPETG-VDATQDIPALSESTTKNCLVPFKKLLQRIVTREDVPPVSCIVS 125

  Fly   134 SGE-KFDLVIMEAVQTEALFGLIQHF-GAETIGISSYGTDTH----IDELMGNISPLSYNPLLLS 192
            .|. .|.|.:.|.:....:     || .....|..:|   .|    |::   .:.|:.....|..
plant   126 DGSMSFTLDVAEELGVPEI-----HFWTTSACGFMAY---LHFYLFIEK---GLCPVKDASCLTK 179

  Fly   193 SRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSL--DEVLDSFAL------ 249
                  ::.|.|::       |       :||..::..|..|:..::.  ::::.:|.:
plant   180 ------EYLDTVID-------W-------IPSMNNVKLKDIPSFIRTTNPNDIMLNFVVREACRT 224

  Fly   250 -----MLLG-----QHFSLSYPRPYLPNMIEVGGLHLQQKRKVQP----------LAKELSEFV- 293
                 ::|.     :|..:...:..||.:..:|.|||...|:::.          |.||.:|.:
plant   225 KRASAIILNTFDDLEHDIIQSMQSILPPVYPIGPLHLLVNREIEEDSEIGRMGSNLWKEETECLG 289

  Fly   294 ---EQSEKGVIYFSMGSNIKSKDLPPSTRKMLMQ---TFASVPQRVLWKFEDDQ----------- 341
               .:|...|:|.:.||      :...|...|::   ..|:..:..||....|.
plant   290 WLNTKSRNSVVYVNFGS------ITIMTTAQLLEFAWGLAATGKEFLWVMRPDSVAGEEAVIPKE 348

  Fly   342 -LPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAK 405
             |.|..|...::.|.||..:|:||.|..|:||.|..||:||:..|.|::..|.|.:|..|.:
plant   349 FLAETADRRMLTSWCPQEKVLSHPAVGGFLTHCGWNSTLESLSCGVPMVCWPFFAEQQTNCK--- 410

  Fly   406 QVGYGLSADIWSVNAT--------ELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWT 462
                 .|.|.|.|...        |:..:::||:..        .|.|..|       |:|:.|.
plant   411 -----FSCDEWEVGIEIGGDVKRGEVEAVVRELMDG--------EKGKKMR-------EKAVEWR 455

  Fly   463 EYVLRHKGAKHLRCASRDLDF 483
            .  |..|..| |.|.|..::|
plant   456 R--LAEKATK-LPCGSSVINF 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	111/530 (21%)
Ugt35A1	NP_524314.2	UDPGT	55..526	CDD:278624	108/507 (21%)
UGT85A3	NP_173655.2	Glycosyltransferase_GTB_type	9..478	CDD:299143	113/537 (21%)
UGT85A3	NP_173655.2	MGT	20..459	CDD:273616	104/504 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto4186
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.050