Protein Alignment Ugt35A1 and ugt1b4

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001166239.2
• Gene: ugt1b4 / 795050
• ZFINID: ZDB-GENE-080227-13
• Length: 533
• Species: Danio rerio
• Alignment Length: 557
• Identity: 160/557 - (28%)
• Similarity: 269/557 - (48%)
• Gaps: 66/557 - (11%)

  Fly    10 LGI---LLIGLIWLFAANADEGVQSSRI----LAVFPFPGRSQYIFAEQFMKELAHRGHNVTVIN 67
            ||:   |::|::  .:|..|:.:..:..    |.|.|..| |.:...:...:|:..|||.|.|:.
Zfish     7 LGVIICLVVGVV--CSAVVDQKLSRNSSWTGKLLVVPMDG-SHWTGVKAVAEEMGRRGHTVIVVI 68

  Fly    68 TFGSDKNEPNFRVIGAK--------KIHEIMAAFGNADYTQTASQWQMLTMTTQFL--------N 116
            ...|.:..|....|..|        .|::||....|   ...||:..:|...|..:        :
Zfish    69 PEISMRLGPGKHYITKKFPVQYKQDLINQIMVEHVN---EVAASEQSLLKTVTSIMYRFGKIIDH 130

  Fly   117 LLTT--SILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMG 179
            .::|  |:..:..:.:.|.. :.||.|:......         .||    |.:|........::.
Zfish   131 FISTSESLFQEQELIEFLRD-QNFDAVLTNPAMP---------MGA----ILAYNLSVPAVYMLR 181

  Fly   180 NI----------SPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP 234
            .|          :|.||.|...:..:::|.|.:||:|...:.:..|..|:: |.|..::.:| |.
Zfish   182 GIMCESKATACPNPPSYIPRFFTQISDRMTFSERVINTLVSLLEPLMCRLM-LGSFEEMTSK-FL 244

  Fly   235 TARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EK 298
            ....|:.|:|.:.|:.|:...|:|.:|:|.:||||.:||::.:.|   .||.||:.|||..| |.
Zfish   245 HRDVSITEILSTAAVWLMRYDFTLEFPKPLMPNMITIGGINCEVK---NPLTKEVEEFVNGSGEH 306

  Fly   299 GVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAH 363
            |::.||:||.:.|  :|.....:..:.|:.:||||||::..:.....|:||.:.||.||.|:|.|
Zfish   307 GIVVFSLGSLVSS--MPKEKADIFFKAFSMIPQRVLWRYTGEIPNNVPENVKLMKWLPQNDLLGH 369

  Fly   364 PNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQ 428
            |..:.||||||.....|.|..|.|::.||:|.||..||.|....|.|:...|..:....|...:.
Zfish   370 PKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGVILSIHDITVETLLDALN 434

  Fly   429 ELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWG 493
            .:::|.||....|..|.:..|:....|:.|::|||:|:|||||.|||.|:.:|:::|:|.||..|
Zfish   435 SVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRPAAHELNWLQYHSLDVIG 499

  Fly   494 LLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAE 530
            .::.|.   |::.:.::||....:.....|.:|.:.:
Zfish   500 FMLLIV---LIVTLAMLKCCSLCWRRCCRKTQKRKED 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	140/487 (29%)
ugt1b4	NP_001166239.2	UDPGT	35..529	CDD:278624	153/521 (29%)