Protein Alignment Ugt35A1 and ugt2a4

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001170804.2
• Gene: ugt2a4 / 791613
• ZFINID: ZDB-GENE-080721-23
• Length: 533
• Species: Danio rerio
• Alignment Length: 571
• Identity: 161/571 - (28%)
• Similarity: 263/571 - (46%)
• Gaps: 99/571 - (17%)

  Fly    17 LIWLFAANADEGVQSSRILAVFPFPGR-SQYIFAEQFMKELAHRGHNVTVINTFGS--------- 71
            |:.|.....|.| .|.|:|.:   ||. |.:......::.|..|.|:|||:.:..|
Zfish     7 LVCLLLCGVDVG-WSGRVLVM---PGEYSHWHNMRAIIEALVDRNHSVTVLVSSSSPTVPHTQKA 67

  Fly    72 -----------DKNEPNFRVIGAKKIHEIMAAFGNADYT-----QTASQ-------WQMLTMTTQ 113
                       ||.|       ||.|.        :|:|     :|.|:       |::::...:
Zfish    68 RFDYHVFKVNMDKEE-------AKVIW--------SDFTHLWMKETDSKLERGFLIWRVMSNFRR 117

  Fly   114 FLNLLTTSILDDAAVKDLLNS-GEK-FDLVIMEAVQTEALFGLIQHFGAETIGIS---------S 167
            ....:..|:|.:   .|||.. ||. :|::..:.:..      .....|:|:.|.         :
Zfish   118 LAADVCRSLLQN---DDLLQMLGESHYDVLFSDPMMP------CSDLMAQTLNIPQVISLRLTFA 173

  Fly   168 YGTDTHIDELMGNI-SPLSYNP--LLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLY 229
            |    ..:.:.|.: :|.||.|  .|....|::|.|.:||.|:.   :.::|..:..|.:...:.
Zfish   174 Y----TFERMCGQMPAPPSYVPAVALTDHLTDRMSFMERVENML---LYFIHTTVFRLNTMLTVD 231

  Fly   230 AKYFPTARK--SLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEF 292
            ..|.....|  ::.|.:....:.|:..::...||||:.||...|||||.   :..:||:||:.||
Zfish   232 RLYTEIRGKPTTMCETMGKADIWLIRTYWDFEYPRPFPPNFKFVGGLHC---KPAKPLSKEMEEF 293

  Fly   293 VEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFP 356
            |:.| :.||:.||:||.|  |:|.......:......:||:|:|::..........|..|..|.|
Zfish   294 VQSSGDHGVVVFSLGSMI--KNLTSERANTIAAALGQIPQKVVWRYSGKTPETLAPNTKIYDWIP 356

  Fly   357 QPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNAT 421
            |.|:|.||..|.||||||.....|:||.|.|::|||:|.||..|:...|..|..:..||.::.:.
Zfish   357 QNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGLPLFADQPDNLLHMKTKGAAVVLDINTLESK 421

  Fly   422 ELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQF 486
            :|...::.:|:||||..:....|::..||....|::|::|.|:|:|:|||||||..:.:|.:.|:
Zfish   422 DLVDALKTVLNNPSYKESIMRLSRIHHDQPMKPLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQY 486

  Fly   487 HGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ 537
            |.||....|::|   :.||..:.:|....:|...:.|.|..|      |||
Zfish   487 HCLDVAAFLLSI---AALITFLWVKACCFLFRRCVRKTRPER------KTQ 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	140/504 (28%)
ugt2a4	NP_001170804.2	UDPGT	21..520	CDD:278624	150/540 (28%)