DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35A1 and ugt8

DIOPT Version :9

Sequence 1:	NP_524314.2	Gene:	Ugt35A1 / 41334	FlyBaseID:	FBgn0026315	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_002934292.2	Gene:	ugt8 / 779534	XenbaseID:	XB-GENE-960667	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	526	Identity:	145/526 - (27%)
Similarity:	252/526 - (47%)	Gaps:	50/526 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 IWLFAANADEGV-QSSRILAVFPFPGRSQ-YIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRV 80
            :|:..     || ::::||.|.|....|. ||| :.....|..:||....:.:.|.|
Frog    11 LWIAV-----GVTKAAKILIVPPIMFESHLYIF-KTLASALHEQGHQTVFLASEGRD-------- 61

  Fly    81 IGAKKIHEIMAAFG--NADYTQTASQWQMLTM-TTQFLNLLTTSILD------DAAV--KDLLN- 133
            |.....:::....|  |:..:....|.:|:.: :.:|..|....|||      |..|  .||:.
Frog    62 IPQSSHYQVQRYPGIFNSSTSDNFLQSKMMNIFSGRFTALELFDILDHYSKNCDIMVGNLDLMRR 126

  Fly   134 -SGEKFDLVIMEAVQTEALFGLIQHFGAETIGI--SSYGTDTHIDELMGNISPLSYNPLLLSSRT 195
             ..|:|||::   |....:.|.:.   |..:.:  :.:.|.......:|..:||:|.|...|..|
Frog   127 LKQEQFDLLL---VDPNEMCGFVI---ANILDVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSMLT 185

  Fly   196 EQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARKSLDEVLDSFALMLLGQHFSLSY 260
            :.|:..||:.|.|...:..:....:.||....:..||...:.:|:.|::....|.:|....:|.:
Frog   186 DNMNLLDRIKNTFVYLISRIGVNFLVLPKYDRIMQKYNIFSTRSMYELVQGSCLWMLCTDIALEF 250

  Fly   261 PRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQ-SEKGVIYFSMGSNIK--SKDLPPSTRKML 322
            |||.|||::.|||:   ..:.|.||.::|..:|:. .|.|.:..|.|:.:|  |:|:    ...|
Frog   251 PRPTLPNVVYVGGI---LTKPVSPLPQDLQTWVDNVDENGFVLVSFGAGVKYLSEDI----ANKL 308

  Fly   323 MQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKP 387
            ....|.:||:|:|:|...:.....:|..:.:|.||.|:|.||.:|.|::||||....|::|.|.|
Frog   309 AGALARLPQKVIWRFSGTKPRNLGNNTKLIEWIPQNDLLGHPKIKTFLSHGGLNGIFEAMYHGVP 373

  Fly   388 ILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKE 452
            ::|:|:|.|.:..:.|.:..|.|:..:...:....|...:.|::.|.||...|...|.:.:||..
Frog   374 VVGIPLFGDHYDTMTRVQAKGMGILLEWKKITEDTLFASLTEVIHNQSYQQQAVKLSTIHKDQPG 438

  Fly   453 TALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVF 517
            ..:.||::|..|:|||.||.|||.|..::.|.|:..||...||:.:..::...:.:|.|.:::
Frog   439 HPVSRAVYWINYILRHNGADHLRAAIHNVSFYQYFLLDVVLLLLFVVTIAWYFISMLAKYMRK-- 501

  Fly   518 VSLISK 523
             |:.||
Frog   502 -SMRSK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	130/474 (27%)
Ugt35A1	NP_524314.2	UDPGT	55..526	CDD:278624	134/487 (28%)
ugt8	XP_002934292.2	Glycosyltransferase_GTB-type	21..472	CDD:415824	132/472 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9349
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.000