Protein Alignment Ugt35A1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 534
• Identity: 153/534 - (28%)
• Similarity: 250/534 - (46%)
• Gaps: 73/534 - (13%)

  Fly     7 VTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTV------ 65
            :.||.:||..|.|         .:..::| |||..| |.::.....::||..|||...|
  Rat    10 LAGLLLLLYALPW---------AEGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVT 63

  Fly    66 ----------INTFGSDKNEPNFRVIGAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTT 120
                      :.|:........||   .:.:..|...|...:|.:|..:      |::.|..::|
  Rat    64 VHIKEEDFFTLQTYPVPYTRQGFR---QQMMRNIKVVFETGNYVKTFLE------TSEILKNIST 119

  Fly   121 -------SILDDAAVKDLLNSGEKFDLVIME-AVQTEALFGLIQHFGAETIGISSY---GTDTHI 174
                   ::|.:.::...||| ..||:|:.: .:...|:  |.::.|..|:....|   |.|:..
  Rat   120 VLLRSCMNLLHNGSLLQHLNS-SSFDMVLTDPVIPCGAV--LAKYLGIPTVFFLRYIPCGIDSEA 181

  Fly   175 DELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARK- 238
            .:..   .|.||.|.||:..::.|.|..||.|:.....:   |.|.|..     :.:|...|.:
  Rat   182 TQCP---KPSSYIPNLLTMLSDHMTFLQRVKNMLYPLAL---KYICHFS-----FTRYESLASEL 235

  Fly   239 -----SLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-E 297
                 ||.|||...::.|....|...||||.:|||:.:||::...|:   ||::|...:|..| |
  Rat   236 LQREVSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIKK---PLSQEFEAYVNASGE 297

  Fly   298 KGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILA 362
            .|::.||:||.:  .::|......:.:....:||.|||::...:......|..:.||.||.|:|.
  Rat   298 HGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLG 360

  Fly   363 HPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLI 427
            ||..:.||||.|.....|.|..|.|::.:|:|.||..|.:|.:..|.|::.::..:.|.:|...:
  Rat   361 HPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENAL 425

  Fly   428 QELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTW 492
            :.:::|.||.......|.|.:|:....|:.|::|.|||:|||||.|||.|:.||.:.|:|.||..
  Rat   426 KTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVI 490

  Fly   493 GLLIAITFVSLLIV 506
            |.|:||....:.||
  Rat   491 GFLLAIVLTVVFIV 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	132/488 (27%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	147/509 (29%)