Protein Alignment Ugt35A1 and Ugt2a2

DIOPT Version :9

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001019319.1
• Gene: Ugt2a2 / 552899
• MGIID: 3576095
• Length: 528
• Species: Mus musculus
• Alignment Length: 554
• Identity: 170/554 - (30%)
• Similarity: 274/554 - (49%)
• Gaps: 88/554 - (15%)

  Fly     4 IFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVI-- 66
            ||.:|...|:|.|.:                 .|:|..| |.::..:..::||..|.|:|||:
Mouse    10 IFHLTLAEIVLSGNV-----------------VVWPTDG-SHWLNIKILLEELVQRNHSVTVLAP 56

  Fly    67 --NTFGSDKNEP--NFRVIGA----KKIHEI---MAAFGNADYTQTASQWQMLTMTT---QFLNL 117
              ..|.:.:.:.  ||..|..    .||.||   |.|.. .|:..|.     |||.|   :..||
Mouse    57 SETLFINSRLDAFINFEEIPVSYTKSKIDEIIEHMIALW-LDHRPTP-----LTMWTFYKELGNL 115

  Fly   118 LTT----------SILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGI------- 165
            |.|          .:|::..|.:.|..| .||:::.:.|.      :.....|..:||
Mouse   116 LATFYTTNKQMCDGVLNNPTVMERLQKG-GFDVLLADPVT------MCGELVALKLGIPFVYTLR 173

  Fly   166 --SSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVM-WLHKRIVHLPSQRD 227
              .::..:.|..::.   :|:||.|..||..|:||.|.:||.|:...|:. ::.|  .:......
Mouse   174 FSPAFTVERHCGKIP---APISYVPAALSELTDQMSFGERVKNIISYSLQDYIFK--TYWGEWNS 233

  Fly   228 LYAKYF--PTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELS 290
            .|:|..  ||   :|.|.:....:.|:..::...:|||||||...|||||.   :..:||.||:.
Mouse   234 YYSKVLGRPT---TLCETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC---KPAKPLPKEME 292

  Fly   291 EFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEK-PDNVFISK 353
            |||:.| |.|::.||:||.:  |:|......::....|.:||:|||::: .::|:. ..|..:..
Mouse   293 EFVQTSGEHGIVVFSLGSMV--KNLTDEKANLIASALAQIPQKVLWRYK-GKIPDTLGSNTRLFD 354

  Fly   354 WFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSV 418
            |.||.|:|.||..:.||||||.....|:||.|.|::|:|:|.||..|:...|..|..:..::.::
Mouse   355 WIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTM 419

  Fly   419 NATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDF 483
            .:::|...::.:::.|||...|...|::..||....|:||::|.|:|:|||||||||.|:.||.:
Mouse   420 TSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSW 484

  Fly   484 IQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVF 517
            .|:|.||..|.|:|....::|:|.   ||...:|
Mouse   485 FQYHSLDVIGFLLACVASAILLVA---KCCLFIF 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	146/494 (30%)
		UDPGT	55..526	CDD:278624	160/503 (32%)
Ugt2a2	NP_001019319.1	UDPGT	22..516	CDD:278624	165/542 (30%)
		egt	<267..487	CDD:223071	87/225 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840200
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.790