Protein Alignment Ugt35A1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 528
• Identity: 150/528 - (28%)
• Similarity: 250/528 - (47%)
• Gaps: 66/528 - (12%)

  Fly    17 LIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGS-DKNEPNFRV 80
            |:.:|..:|.   .:.|:| |||..| |.::.....:::|..:||.|.||....| ...|.:|..
Mouse    18 LLCVFGPSAS---HAGRLL-VFPMDG-SHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSFYT 77

  Fly    81 I-------GAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKF 138
            :       ..:.:...:...|...:.|.:.   :|.:...::.:...|.:..|....||::.|
Mouse    78 LRKFPVPFQKENVTATLVELGRTAFNQDSF---LLRVVKIYMKVKRDSSMLLAGCSHLLHNAE-- 137

  Fly   139 DLVIMEAVQTEALF-------GLI--QHFGAETI--------GISSYGTDTHIDELMGNISPLSY 186
            .:..:|....:||.       |.|  |:....|:        .:.|..|...:        ||||
Mouse   138 FMASLEESHFDALLTDPFLPCGSIVAQYLTVPTVYFLNKLPCSLDSEATQCPV--------PLSY 194

  Fly   187 NPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFPTARK------SLDEVLD 245
            .|..||..:::|:|..||.||..|.......|:|        |:.|...|.:      ::.::|.
Mouse   195 VPKSLSFNSDRMNFLQRVKNVLLAVSENFMCRVV--------YSPYGSLATEILQKEVTVQDLLS 251

  Fly   246 SFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSNI 309
            ..::.|:...|...||||.:|||:.:||::..||:   ||::|...:|..| |.|::.||:||.:
Mouse   252 PASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQKK---PLSQEFEAYVNASGEHGIVVFSLGSMV 313

  Fly   310 KSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGG 374
              .::|......:.:....:||.|||::...:......|..:.||.||.|:|.||..:.||||.|
Mouse   314 --SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSG 376

  Fly   375 LLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAA 439
            .....|.|..|.|::.:|:|.||..|.:|.:..|.|::.::..:.|.:|...::.:::|.||...
Mouse   377 SHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKEN 441

  Fly   440 AQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLL 504
            ....|.|.:|:....|:.|::|.|||:|||||.|||.|:.||.:.|:|.||..|.|:||.   |.
Mouse   442 IMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIV---LT 503

  Fly   505 IVVILIKC 512
            :|.|:.||
Mouse   504 VVFIVFKC 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	130/486 (27%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	147/513 (29%)