Protein Alignment Ugt35A1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_775417.1
• Gene: Ugt2b1 / 286954
• RGDID: 708541
• Length: 529
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 164/555 - (29%)
• Similarity: 269/555 - (48%)
• Gaps: 97/555 - (17%)

  Fly    13 LLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEP- 76
            |||.||..|...|     ..::| |:| ...|.:|..:..:.|||.|||.|||:.:..|...||
  Rat    10 LLIQLICYFRPGA-----CGKVL-VWP-TEYSHWINIKIILNELAQRGHEVTVLVSSASILIEPT 67

  Fly    77 -----NFRVIGAKKIHEIMAAFGNADYT------------QTASQW----QMLTMTTQFL----N 116
                 ||      :|:.:..:..:.:|:            :|.|.|    :|..:..::.    |
  Rat    68 KESSINF------EIYSVPLSKSDLEYSFAKWIDEWTRDFETLSIWTYYSKMQKVFNEYSDVVEN 126

  Fly   117 LLTTSILDDAAVKDLLNSGEKFDLVIMEAV-----------QTEALFGLIQHFGAETIGISSYGT 170
            |....|.:.:.:|.|  .|.:||:::.:||           :|..::.|            .:..
  Rat   127 LCKALIWNKSLMKKL--QGSQFDVILADAVGPCGELLAELLKTPLVYSL------------RFCP 177

  Fly   171 DTHIDELMGNIS-PLSYNPLLLSSRTEQMDFKDRVMNVFEASV--MWLHKRIVHLPSQRDLYAKY 232
            ....::..|.:. |.||.|::||..:::|.|.:||.|:.:...  .|..      |.:...::::
  Rat   178 GYRCEKFSGGLPLPPSYVPVVLSELSDRMTFVERVKNMLQMLYFDFWFQ------PFKEKSWSQF 236

  Fly   233 F------PTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSE 291
            :      ||   :|.|::....:.|:...:.|.:|.|:|||...|||||.   :..:||.:|:.|
  Rat   237 YSDVLGRPT---TLTEMMGKADIWLIRTFWDLEFPHPFLPNFDFVGGLHC---KPAKPLPREMEE 295

  Fly   292 FVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPD----NVFI 351
            ||:.| |.||:.||:||.:  |:|......::....|.:||:|:|:|:.    :|||    |..:
  Rat   296 FVQSSGEHGVVVFSLGSMV--KNLTEEKANVVASALAQIPQKVVWRFDG----KKPDTLGSNTRL 354

  Fly   352 SKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIW 416
            .||.||.|:|.||..|.|:.|||.....|:||.|.||:|:|:|.||..|:......|..:..|..
  Rat   355 YKWIPQNDLLGHPKTKAFVAHGGTNGIYEAIYHGIPIVGIPLFADQPDNINHMVAKGAAVRVDFS 419

  Fly   417 SVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDL 481
            .::.|.|...::.::::|||...|...|::..||....|:||::|.|||:|||||||||....||
  Rat   420 ILSTTGLLTALKIVMNDPSYKENAMRLSRIHHDQPVKPLDRAVFWIEYVMRHKGAKHLRSTLHDL 484

  Fly   482 DFIQFHGLDTWG-LLIAITFVSLLIVVILIKCLQR 515
            .:.|:|.||..| ||:.:..|..:|....:.|.::
  Rat   485 SWFQYHSLDVIGFLLLCVVGVVFIITKFCLFCCRK 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	144/505 (29%)
Ugt2b1	NP_775417.1	UDPGT	24..527	CDD:278624	157/536 (29%)