Protein Alignment Ugt35A1 and Ugt2b36

DIOPT Version :9

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001025038.1
• Gene: Ugt2b36 / 231396
• MGIID: 3576103
• Length: 530
• Species: Mus musculus
• Alignment Length: 534
• Identity: 152/534 - (28%)
• Similarity: 258/534 - (48%)
• Gaps: 84/534 - (15%)

  Fly    44 SQYIFAEQFMKELAHRGHNVTVI----NTFGSDKNEPNFRVIGAKKIHEIMAAFGN----ADYTQ 100
            |.::..:..:.||..:||.|||:    :.|...|..|..      |......:|.|    ..:.:
Mouse    34 SHWMNIKIILDELKQKGHEVTVLRPSTSIFLDPKKSPGL------KFETFPTSFSNDVMEIIFAK 92

  Fly   101 TASQW--QMLTMTTQFLNLLTTSILDD------AAVKDLLNSGE--------KFDLVIMEAVQTE 149
            ...:|  ::...|....:.|..:|.|:      ...||.:::.:        |||:::.:|:
Mouse    93 AVERWTYEVPRDTCLSYSPLLQNIFDEYSDYCLTLCKDTVSNKQLMAKLQESKFDVILSDAI--- 154

  Fly   150 ALFGLIQHFGAETIGIS-----SYGTDTHIDELMGNIS-PLSYNPLLLSSRTEQMDFKDRVMNVF 208
               |......||.:.|.     .:....::::..|.:. |.||.|::||..:.||.||:||.|:
Mouse   155 ---GPCGELIAELLQIPFLYSLRFSPGYYLEKYSGGLPLPPSYVPVILSGLSGQMTFKERVKNM- 215

  Fly   209 EASVMWLHKRIVHLPSQRDLYAKYFPTARK---------------SLDEVLDSFALMLLGQHFSL 258
               :..|:            :..:|.|.|:               :|.|.:....:.|:..::.|
Mouse   216 ---ICMLY------------FDFWFQTFREKKWDQFYSETLGRPTTLIETMGKAEMWLIRSYWDL 265

  Fly   259 SYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKML 322
            .:|.|.|||:..|||:|.   :..:||.||:.:||:.| |.||:.||:||.:  .::.......:
Mouse   266 EFPHPTLPNVYYVGGVHC---KPAKPLPKEMEDFVQSSGEHGVVVFSLGSMV--SNMTEEKANAI 325

  Fly   323 MQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKP 387
            ....|.:||:|||:|:.........|..|.||.||.|:|.||..|.||||||.....|:|:.|.|
Mouse   326 AWALAQIPQKVLWRFDGKTPATLGPNTRIYKWLPQNDLLGHPKTKAFITHGGANGLYEAIHHGIP 390

  Fly   388 ILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKE 452
            ::|:|:|.:||.|:......|..::.:|.:::.::|...::|::.||.|...|...|.:..||..
Mouse   391 MIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDLLNALEEVIDNPFYKENAMWLSTIHHDQPM 455

  Fly   453 TALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIA-ITFVSLLIVVILIKCLQRV 516
            ..|:||::|.|:|:|||||||||..:.:|.:.|:|.||..|.|:| :||    ||.:::||...|
Mouse   456 KPLDRAVFWIEFVMRHKGAKHLRPLAYNLTWYQYHSLDVIGFLLAFVTF----IVALIVKCFLFV 516

  Fly   517 FVSLISKIRKNRAE 530
            :...:.|.:|.:.|
Mouse   517 YRFFVKKEKKMKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	131/475 (28%)
		UDPGT	55..526	CDD:278624	149/517 (29%)
Ugt2b36	NP_001025038.1	egt	8..506	CDD:223071	144/508 (28%)
		UDPGT	24..527	CDD:278624	150/529 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840429
Domainoid	1	1.000	259	1.000	Domainoid score	I1975
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2975
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm42461
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.690