DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35A1 and ugt-55

DIOPT Version :9

Sequence 1:	NP_524314.2	Gene:	Ugt35A1 / 41334	FlyBaseID:	FBgn0026315	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	502	Identity:	132/502 - (26%)
Similarity:	197/502 - (39%)	Gaps:	111/502 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVI-NTFGSD-KNEPNFR 79
            ||::| .|......|.|||...|....|...|.......|..|||||.|: |...|| .|:.:.:
Worm     9 LIFIF-LNYGTPCLSLRILVYSPRMIPSHVAFVANIANLLGQRGHNVVVVDNVLRSDISNKLDLK 72

  Fly    80 VIGAKKIHEIMAAFGN-----ADYTQTASQWQMLTMTTQ---FLNLLTTSILDDAAVKDLLNSGE 136
            ||  :|:.::..: .|     ||.:...:.|.|.....:   .:..|....|:..  |.|::
Worm    73 VI--EKVVKVETS-ANVAKLLADQSIPINFWSMRNEPEEQKKVMKQLGIIFLEQC--KYLVS--- 129

  Fly   137 KFDLVIMEAVQTEALFGLIQHFGAETIGI------------SSYGTDTHIDELMGNISPLSYNPL 189
            |.:.|..|....|..||:.:.|....|||            ||.|....::|.:| ||....:..
Worm   130 KEETVFNELKHLEFDFGIHEVFDICGIGIFEKLGIRKSVILSSTGMRDIVNEALG-ISSQLQDAS 193

  Fly   190 LLSSRTEQMDFKDRVMNV-FEASVMWLHKRIVHLPSQRDLYAKYFPTARKSLD---EVLDSFA-- 248
            :||.....:.|.....|: |.::                 :..:|....|:|:   |...||.
Worm   194 ILSDYGNSIPFYGIRRNLKFHSA-----------------WRNFFEVQSKTLEPLFETTSSFENL 241

  Fly   249 -----LMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEK--GVIYFSMG 306
                 ||.|..|......||:...:.|:||:..   :...||.   :|::....|  .:|..|.|
Worm   242 LRFSNLMFLNTHELADAHRPWSRRVHEIGGISF---KFPMPLK---NEYINLFNKYNSIILVSFG 300

  Fly   307 SNIKSKDLPPSTRKMLMQTFASVPQRV-LWKFE-DDQLPE--KPDNVFISKWFPQPDILAHPNVK 367
            :...|..:|...:..|:.||...|..: :||:| ||:..:  |..||...|:.||.|:|....:|
Worm   301 TTTPSFLMPEKYKNTLINTFQRFPDFLFIWKYEKDDEFTQKNKKGNVVFKKFLPQVDLLESRKIK 365

  Fly   368 LFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLS 432
            |||||||..|.:|:.:.....|..|:|.|||.|.|.|.:  .|||           ..|:::.|:
Worm   366 LFITHGGQNSLLETFHSNTRTLITPLFGDQHRNAQIALE--NGLS-----------HVLLKDQLA 417

  Fly   433 NPS--YAA------------------------AAQTKSKLFRDQKET 453
            |..  |||                        |.||...||.|..|:
Worm   418 NEELVYAAIKQGTESNKKLDDNLLKLSSNLKNAKQTSENLFLDTVES 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	egt	19..474	CDD:223071	130/500 (26%)
Ugt35A1	NP_524314.2	UDPGT	55..526	CDD:278624	121/464 (26%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	104/395 (26%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	51/157 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810