Protein Alignment Ugt35A1 and ugt-14

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_504316.1
• Gene: ugt-14 / 186767
• WormBaseID: WBGene00019233
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 147/547 - (26%)
• Similarity: 231/547 - (42%)
• Gaps: 93/547 - (17%)

  Fly    29 VQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVI--------NTFGSDKNEP--------- 76
            :....||...|....|...|..|....:|..|||||:.        ||.|..||..
 Worm    16 ISCKNILIFNPIFAFSHVKFVTQMADIIADHGHNVTLFQPYHIAMKNTEGLVKNRKVNIINYYPH 80

  Fly    77 NFRVI-GAKKIHEIMAAFGNADYTQTA--SQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKF 138
            :|..| ||  :.|..:...::.....|  |.:.|.....:......|.:|.|.::.:.|.| .||
 Worm    81 DFNTISGA--MPETFSGLWDSKLLNNAILSAYAMPKAIGRVFEKTATQLLQDESILEELKS-RKF 142

  Fly   139 DLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDR 203
            ::||.||.:...:: |.......:|.|.|.......:...|..|.|.|.|....||  ::.|.||
 Worm   143 EVVISEAFEITEMY-LAHLLKIPSIPIKSSVRYPAFNNAFGQPSSLGYLPQQGLSR--EIGFLDR 204

  Fly   204 VMNVF-------------EASVMWLHKRIVH-LPSQRDLYAK---YFPTARKSLDEVLDSFALML 251
            ::.|:             |..|.::.|.:.| :|..|||..:   |...:...||     ||:
 Worm   205 LLEVYDHYFLVKMQERLNEYQVNFIEKALGHPVPHWRDLVKESPIYITNSNPYLD-----FAV-- 262

  Fly   252 LGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQP--LAKELSEFVEQSEKGVIYFSMGSNIKSKDL 314
                       |....::.|||:.:..|:...|  |..|..|.:::.:..|: .|.||.::|.|:
 Worm   263 -----------PTTATVVHVGGITMDMKKLKNPQQLPDEYEEILQERDSTVL-ISFGSVVRSCDM 315

  Fly   315 PPSTRKMLMQTFASVPQ-RVLWKFEDDQL---PEKPDNVFISKWFPQPDILAHPN-VKLFITHGG 374
            |.:.:..:::.|.|:|. ..:||:|.|.:   .:.|.||.:.||.|||.:||... ||.|:||||
 Worm   316 PENFKAGVVKMFESLPDITFIWKYEKDDVEFQKKLPKNVHLKKWVPQPSLLADKRFVKRFVTHGG 380

  Fly   375 LLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSAD-IWSVNATELTPLIQELLSNPSYAA 438
            |.||:|..|.|||.|.:|||.||..|.....:.|..:..| :...:..:.|..::|::.||.|..
 Worm   381 LGSTMEVAYTGKPALMVPIFADQFNNANMLARHGGAIPYDKLDLADGEKFTKTVREMVINPKYND 445

  Fly   439 AAQTKSKLFRDQK-ETALERAIWWTEYVLRHKGAKHLRCASRDLDF----IQFHGLDTWGLLIAI 498
            .|:....:..:|. :..|..             .|||..|   ::|    .|...::..| ||..
 Worm   446 NAKVLLIILLNQPIDPKLNL-------------MKHLEFA---MEFPNLRSQIPEINNAG-LIGY 493

  Fly   499 TFVSLLIVVILIKCLQ-RVFVSLISKI 524
            .::.::...||..||. .:|.:||.||
 Worm   494 YYLDIIAFFILFACLALYLFTNLIFKI 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	130/490 (27%)
ugt-14	NP_504316.1	GT1_Gtf-like	20..450	CDD:340817	127/454 (28%)