Protein Alignment Ugt35A1 and ugt-42

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_503278.2
• Gene: ugt-42 / 185168
• WormBaseID: WBGene00017959
• Length: 527
• Species: Caenorhabditis elegans
• Alignment Length: 583
• Identity: 134/583 - (22%)
• Similarity: 236/583 - (40%)
• Gaps: 126/583 - (21%)

  Fly    13 LLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPN 77
            |||.||::|..:   .:.....|.|.|..|.|...|..:....|...||||||::...|.|
 Worm     3 LLILLIFVFLIS---NISGFNYLVVSPAFGHSHSTFMGKLADALTEAGHNVTVLSIIVSSK---- 60

  Fly    78 FRVIGAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKF---D 139
                           |.|..||:         :|...:.:.||:..|..|.....|...::   :
 Worm    61 ---------------FRNISYTK---------LTKDIVVVETTNEQDQQAENMENNDFSRYWTQE 101

  Fly   140 LVIMEAVQTEALFGLIQHFGAET------------------------------------------ 162
            ..::|.:.:..:|..:...|.||
 Worm   102 GTLLETIPSYLMFTKMSDHGYETFRNHALPQMEYLKSHRPRYDAVFFESYLHTGKAIQEYLEIPV 166

  Fly   163 -IGISSYGTDTHIDELMGN-ISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQ 225
             :.::|...|..:.||:|. :|| ||.....::....|:|::||:|...   .:|.:.::..|:.
 Worm   167 FLPVTSLTHDYRLAELIGEPVSP-SYLSGYFTNFGNIMNFQERVINTLS---YYLAQILISSPNW 227

  Fly   226 RDLYAKYFPTARKSLDEVLDS----FALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLA 286
            :.|       ...|.|.:::|    ...:.:..:..:.:|||.|...||:||:.:.        |
 Worm   228 KTL-------QDPSKDLLVESEYYRAPYVFINSNPYIDFPRPLLSKTIEIGGITVD--------A 277

  Fly   287 KEL-SEFVEQSEKGV-------IYFSMGSNIKSKDLPPSTRK---MLMQTFASVPQRVLWKFEDD 340
            ..| ||.|:::...:       :..|.|:..||..:|.|.:.   .:|::|.:|  ..:||:|.:
 Worm   278 DALKSEKVDETWNNILKRRPHNVLISFGTMFKSIHMPDSYKNNMVKVMKSFKNV--TFIWKYESE 340

  Fly   341 Q--LPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQR 403
            :  .....:|:...||.||..:||...:..|.|||||.|..|..|.|||.|..|:|.||   |:.
 Worm   341 ETSFANGAENIIFKKWTPQTALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQ---VRN 402

  Fly   404 AKQVG-YGLSADIWSVNATELTPL---IQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEY 464
            :|.:. :..|.:|...|......|   :..:|.:.|||..|:..:|....|.....|..:...|:
 Worm   403 SKMLSRHNGSIEISKFNLESYNTLRSALHSILFDESYAENAEKLAKKLEFQPAKPKELFVRHAEF 467

  Fly   465 VLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKN 527
            ..|......|.|..|.:.|..:|.||   :::.:|...:|:::.|:..::::..||..|::::
 Worm   468 AARFGEQPALDCNLRTMGFATYHLLD---VVVCLTSFVVLVILSLVVIIRKIVQSLAIKMKRD 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	116/522 (22%)
ugt-42	NP_503278.2	GT1_Gtf-like	20..464	CDD:340817	113/495 (23%)