Protein Alignment Ugt35A1 and ugt-18

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_506209.2
• Gene: ugt-18 / 179759
• WormBaseID: WBGene00013900
• Length: 533
• Species: Caenorhabditis elegans
• Alignment Length: 543
• Identity: 136/543 - (25%)
• Similarity: 240/543 - (44%)
• Gaps: 80/543 - (14%)

  Fly    33 RILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPNFRV-----IGAKKIHEIMAA 92
            ::|...|..|.|...|..:....|...|||||::        .|.:.:     :|:||:.::: .
 Worm    19 KVLVFNPAYGASHSNFLGKISDILIDAGHNVTML--------IPEYLITKKDFVGSKKVKDVV-R 74

  Fly    93 FG------------NADYTQTASQWQMLTMTTQFLNLLTTSILDDAAV----------KDLLN-- 133
            .|            ..::...|..|:   |..:.::|:|.....:.|:          ||:::
 Worm    75 IGRDERAGKLFEEEGIEHMGRARVWR---MDPEMMSLVTIVGSMNLAIGYQCEYIFQQKDIIDRL 136

  Fly   134 SGEKFDLVIMEAVQTEAL----FGLIQHFGAETI--GISSYGTDTHIDELMGNISPLSYNPLLLS 192
            ..|.|||.|     ||:|    |.|..|.|.:.:  ..|:...|. :....|..:.:||.|.|.|
 Worm   137 RNEHFDLAI-----TESLFACPFALFDHIGIKNVINAESNLFKDA-VKYAHGEPAAISYYPGLFS 195

  Fly   193 SRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDL-YAKYFPTARKSLDEVLDSFALMLLGQHF 256
            ...::|.|..||.|:.   .|...|.:.....:::| ..|.:....::.:::....|..|:..:.
 Worm   196 PHDDKMSFVARVKNMI---TMLFTKYLYGSRYEKELEMIKPYYNGTETWEDLFTGVAFNLINSNQ 257

  Fly   257 SLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEKGVIYFSMGSNIKSKDLPPSTRKM 321
            .:.||.|.||..:.|||:.:........|:.|.:..:...::.|: .|.|||..|.::|...:|.
 Worm   258 YIDYPSPALPKTVFVGGMQVNTNEAKTKLSDEWNNILNIRKQNVL-ISFGSNAFSSEMPEEFKKS 321

  Fly   322 LMQTFASVPQ-RVLWKFED------DQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTI 379
            .:..|.::|: ..:||:|:      ..||    ||.::.|.||.|:||...:.||:|||||.||:
 Worm   322 FLYVFGNMPEITFIWKYEEANATLTSHLP----NVKLTTWMPQNDLLADDRLTLFVTHGGLGSTM 382

  Fly   380 ESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATE-LTPLIQELLSNPSYAAAAQTK 443
            |..|.|||.|.:|:..||..|....|:.|..|......:..:| |....:.:|:...|:..||..
 Worm   383 ELAYQGKPALIIPLMADQPRNAHMLKRHGGCLQYHKTMLGDSEQLLKAFKTVLTERKYSENAQRL 447

  Fly   444 SKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVV- 507
            :::.|||..:..:..:...|:.:.|.....|....|.|:..||:..|   :..:|..::||::|
 Worm   448 ARILRDQPVSPKDLVLKHCEFAVEHGALNSLNSRGRYLNTFQFYSFD---IASSIVMLALLVLVF 509

  Fly   508 ------ILIKCLQRVFVSLISKI 524
                  .:.|.:.|:|:|..:|:
 Worm   510 IYFTLLFIFKLVARIFLSQKTKM 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	121/484 (25%)
ugt-18	NP_506209.2	GT1_Gtf-like	18..465	CDD:340817	119/471 (25%)