Protein Alignment Ugt35A1 and ugt-49

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_505666.2
• Gene: ugt-49 / 179446
• WormBaseID: WBGene00007070
• Length: 525
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 144/548 - (26%)
• Similarity: 242/548 - (44%)
• Gaps: 63/548 - (11%)

  Fly    13 LLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPN 77
            ||:.|:         .|.:.:||...|...||..|...:....|...||:|.:..|    :.||.
 Worm     7 LLLSLL---------AVDAGKILVYSPSISRSHLISNGRIADALVDAGHDVVMFIT----EYEPL 58

  Fly    78 FRVIGAKKIHEI-MAAFGN--ADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEK-- 137
            ....|.||...| |..|..  |:......::.:.:....||..|........|..||:...|:
 Worm    59 TEFTGTKKAKVITMKGFSTKFAEDMDGIGEYLLSSSRLSFLERLMFEKTCTGACDDLMTRREELE 123

  Fly   138 ------FDLVIMEAVQTEALFGLIQHFGAET-IGISSYGTDTHIDELMGNISPLSYNPLL-LSSR 194
                  ||:...|.:....: |::::.|.:. :.||:......:...:|..:|.||.|.: .:..
 Worm   124 QLRAYNFDVAFSEQIDLCGV-GIVRYLGIKNHLWISTTPIMDAVSYNLGIPAPSSYVPTIEENDN 187

  Fly   195 TEQMDFKDRVMNVFEASVMWLHKRIVH---LPSQRDLYAKY---FPTARKSLDEVLDSFALMLLG 253
            .::|||..|..|::    |.:...::|   .....:::.||   ||..|    |:..:.:|..:.
 Worm   188 GDKMDFWQRTFNLY----MKIGSILIHRYGTDGTTEVFRKYIPDFPNVR----EIAANSSLCFVN 244

  Fly   254 QHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQSEKGVIYFSMGSNIKSKDLPPST 318
            ....|..|||.:...|.||||.:.:..|  ||.|:.:..:.:.::||:..|:||.|...|||.:.
 Worm   245 SDEVLDLPRPTITKAIYVGGLGIPKVSK--PLDKKFTNIMSKGKEGVVIISLGSIIPFGDLPAAA 307

  Fly   319 RKMLMQTFASVPQ-RVLWKF-----EDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLS 377
            ::.:::....:.. ..|.|.     ...:|.|...||.:::|.||.|||:||.:|||:.|||:..
 Worm   308 KEGVLRAIQEISDYHFLIKIAKGDNNTKKLVEGIKNVDVAEWLPQVDILSHPRLKLFVMHGGING 372

  Fly   378 TIESIYFGKPILGLPIFYDQHLNVQRAKQVGYG---LSADIW--SVNATELTPLIQELLSNPSYA 437
            .:|:.....|.:.:|:|.||..|.:..::.|.|   |..||.  |...|.||     :|:.|||.
 Worm   373 LVETAIQAVPTVIVPVFADQFRNGRMVEKRGIGKVLLKLDIGYESFKNTVLT-----VLNTPSYK 432

  Fly   438 AAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVS 502
            ..|....|:.||:..:..||...||::.:.|...:.|......|:.|.::.||....::.: ||:
 Worm   433 KNAIRIGKMMRDKPFSPEERLTKWTQFAIDHGVLEELHVEGSRLNTIIYYNLDVIAFVLFV-FVA 496

  Fly   503 LLIVVIL---IKCLQRVFVSLISKIRKN 527
            :|.|.|.   ..|.::...|.|.|.:||
 Worm   497 VLHVFIYAFKFLCCKKRSQSNIKKSKKN 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	125/484 (26%)
ugt-49	NP_505666.2	GT1_Gtf-like	18..443	CDD:340817	117/444 (26%)