Protein Alignment Ugt35A1 and Ugt3a2

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_997099.2
• Gene: Ugt3a2 / 105887
• MGIID: 2146055
• Length: 523
• Species: Mus musculus
• Alignment Length: 524
• Identity: 139/524 - (26%)
• Similarity: 263/524 - (50%)
• Gaps: 47/524 - (8%)

  Fly    29 VQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSD-----KNEPNFRVIGAKKIHE 88
            :::::||.:... ..|.||...:..:.|...||:|..:...|.|     |...:::||..:...:
Mouse    20 LEAAKILTISTL-SASHYILMNRVSQILQGGGHDVIKLLYEGGDIPDFRKENSSYQVINWRLPED 83

  Fly    89 IMAAFGNA------DYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEKFDLVIMEAVQ 147
            ....|.|.      :|....|::..|....|:...|.:.:|....:.:||.. |.||||:::::.
Mouse    84 QQKTFENRWHRLIDEYAYGRSKYHTLLKIHQYFADLCSHLLSRKDIMELLQK-ENFDLVLLDSMD 147

  Fly   148 TEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASV 212
            . ..|.:::..|...:....: ..:::|..:.| :||||.|:..|..|:||||..||.|:    :
Mouse   148 L-CSFLIVEKLGKRFVSFLPF-QFSYMDFGLPN-APLSYAPVYGSGLTDQMDFWGRVKNI----L 205

  Fly   213 MWLHKRIVHLPSQRDLYAKYFPTARKS--------LDEVLDSFALMLLGQHFSLSYPRPYLPNMI 269
            |:.|    ....:||::::|..|.::.        |.::|....|..:...|:|.:.||..||.:
Mouse   206 MFFH----FTKKRRDIFSQYGNTVQEHFAEGSQPVLSDLLLKAELWFVNSDFALDFARPLFPNTV 266

  Fly   270 EVGGLHLQQKRKVQPLAKELSEFVEQ-SEKGVIYFSMG---SNIKSKDLPPSTRKMLMQTFASVP 330
            .||||   ..:.|||:.::|.:|:.| .:.|.:..::|   |.|:||::    .|.:...||.:|
Mouse   267 YVGGL---LDKPVQPIPQDLEDFISQFGDSGFVLVALGSVVSMIQSKEI----IKEMNSAFAHLP 324

  Fly   331 QRVLWKFEDDQLPEK---PDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLP 392
            |.|||..:....|:.   ..||.|..|.||.|:||||:::||:||||:.|.:|:::.|.|::|:|
Mouse   325 QGVLWTCKSSHWPKDVSLAPNVKIMDWLPQIDLLAHPSIRLFVTHGGMNSVMEAVHHGVPMVGIP 389

  Fly   393 IFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALER 457
            .|.||..|:.|.:....|:|..:.::.|......::|::.:..|..||.....:.:....|..:|
Mouse   390 FFGDQPENMVRVEAKNLGVSIQLQTLKAESFLLTMKEVIEDQRYKTAAMASKVIRQSHPLTPAQR 454

  Fly   458 AIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLIS 522
            .:.|.:::|:..||.||:..:....:.:.:.||.:..|:.:|..:|.:.|.::..:.| ::|:..
Mouse   455 LVGWIDHILQTGGAAHLKPYAFQQPWHEQYMLDVFLFLLGLTLGTLWLSVKVLVAVTR-YLSISR 518

  Fly   523 KIRK 526
            |:::
Mouse   519 KVKQ 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	128/470 (27%)
Ugt3a2	NP_997099.2	Glycosyltransferase_GTB-type	24..488	CDD:471961	131/483 (27%)