Protein Alignment Ugt35A1 and ugt1a1

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: XP_004917944.1
• Gene: ugt1a1 / 100489505
• XenbaseID: XB-GENE-998849
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 158/554 - (28%)
• Similarity: 265/554 - (47%)
• Gaps: 66/554 - (11%)

  Fly    12 ILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEP 76
            :|.:|.:.|        :::.::||: |..| |.::.....::.|..||:.|.|:....:....|
 Frog    17 LLFLGRVQL--------IEAEKLLAI-PLDG-SHWLSMRILVESLGQRGNQVVVLAPHSNIHIHP 71

  Fly    77 NFRVI--------GAKKIHEIMAAFGNADYTQTASQWQMLTMTTQFLNLLTTSILDDAAVKDLLN 133
            :...|        ..:.:.|.|....|..:|:.....::..|..:..|:  |.|: .:|.:.||:
 Frog    72 SENYILRTYPVPYSKELLKEQMVKSANDVFTKRPLLDKITNMYQRITNV--TGIV-FSACQHLLH 133

  Fly   134 SGEKFDLVIMEAVQTEAL-FGLIQHF------GAETIGISS----YGTDTHIDELMGNI-SPLSY 186
            |.|     ||:.:|..|. ..||..|      .||.:.:.|    ||....||.|.... |||||
 Frog   134 SKE-----IMQELQESAFDAALIDPFFPCGMIVAEYLHLPSVYLLYGLPCGIDRLATQCPSPLSY 193

  Fly   187 NPLLLSSRTEQMDFKDRVMNVFEASVMW-LHKRIVHLPSQRDLYAKYFPTARKSLD------EVL 244
            .|...:..|:.|.|..|:.|    :::| :...:.:|     ||:.|...|.:.|.      ::.
 Frog   194 VPRHFTGNTDHMSFPQRLKN----ALLWPVDTFLCNL-----LYSPYAQLASEFLHREMTILQLY 249

  Fly   245 DSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSN 308
            ...::.|:...|...||||.:|||:.|||::...:   |.|.:|..:.|..| |.|.:.||:||.
 Frog   250 SQTSVWLMKTDFVFDYPRPLMPNMVFVGGINCVGE---QHLNQEFEKLVNSSGEHGFVVFSLGSM 311

  Fly   309 IKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPDNVFISKWFPQPDILAHPNVKLFITHG 373
            :  .::|.:....:.:...|:||:|.|::.....|...:|..:.||.||.|:||||..:.||||.
 Frog   312 V--SEIPMNKAMDIAEALKSIPQKVFWRYTGKAPPNLGENTHLVKWLPQNDLLAHPKARAFITHA 374

  Fly   374 GLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAA 438
            |.....|.|....|::.:|:|.||..|.:|.:..|.||:.::..:...:|:..::.:::||.|..
 Frog   375 GSHGIYEGICNAVPMVMMPLFGDQMDNAKRIESRGAGLTLNVLHMTPEDLSNAVRAVINNPVYKE 439

  Fly   439 AAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSL 503
            ..|..|.|..|:....|:.|:.|.|:|:|||||.|||.|:.||::.|::.||..|.|:|:...:|
 Frog   440 NIQRMSSLHLDRPIHPLDLAVHWVEFVMRHKGAPHLRPAAHDLNWFQYYSLDVIGFLLAVLLTAL 504

  Fly   504 LIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ 537
            .   |.:||...||...   .::|..:..|.|:|
 Frog   505 F---ISLKCCTFVFRRC---FKRNSKKQRKSKSQ 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	134/482 (28%)
ugt1a1	XP_004917944.1	UDPGT	30..525	CDD:278624	152/524 (29%)