Protein Alignment Ugt35A1 and ugt2b5

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001170816.3
• Gene: ugt2b5 / 100384902
• ZFINID: ZDB-GENE-100402-3
• Length: 527
• Species: Danio rerio
• Alignment Length: 564
• Identity: 167/564 - (29%)
• Similarity: 270/564 - (47%)
• Gaps: 82/564 - (14%)

  Fly    10 LGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGS--- 71
            |.:..:.|:.:|:|.     |...|| |:...| |.:|..:..:..|..|||||||:...|:
Zfish     3 LVVCFLSLLTVFSAG-----QCGNIL-VWYTEG-SHWINLKIVLDTLLDRGHNVTVLVPDGALFM 60

  Fly    72 ---DKNEPNFRVIGAKKIHEIMAAFGNADYTQTASQWQM-----LTMTTQFLNL----------L 118
               :.:..:::.....|..:.|..|  .|.....|.::|     |.:..:|.||          .
Zfish    61 KAKESDRFSYQHFSVSKSAQDMQDF--FDELMRFSVFEMDNSSFLEIQMKFFNLGSQHQDMSLSY 123

  Fly   119 TTSILDDAAVKDLLNSGEKFDLVIMEAVQTEALFGLIQHFGAETIGISSYGT----DTHIDELM- 178
            ...||....:.|.|..| |||:|:.:.:..      .....||.:.:....|    ..|..|.|
Zfish   124 CDGILKSPELMDKLKKG-KFDVVLSDPMYP------CSDIMAEELNVPLVYTFRFSVAHAAERMC 181

  Fly   179 GNI-SPLSYNPLLLSSRTEQMDFKDRVMN-VFEAS------VMWLHKRIVHLPSQRDLYAKYFPT 235
            |.| :|.||.|..:|..|::|.|.:|:.| :|..|      ::|  :|.      .:.|.:||..
Zfish   182 GQIPAPPSYVPGAMSKLTDRMSFTERIFNMLFYLSQDTLSRLIW--RRF------DNYYTEYFGR 238

  Fly   236 ARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKG 299
            : .|..|::....:.|:..::...:|||::||...:||||.   ...:||.|::.|||:.| :.|
Zfish   239 S-TSYCEMMGRADIWLIRTYWDFEFPRPFVPNFKYIGGLHC---TPAKPLPKDMEEFVQSSGDDG 299

  Fly   300 VIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKPD----NVFISKWFPQPDI 360
            ::.|::||.|..  :|......:....|.:||:|||::..    ||||    |..|.||.||.|:
Zfish   300 IVVFTLGSMIDK--VPKEMSNRIASALAQIPQKVLWRYGG----EKPDTLGENTRIYKWMPQNDL 358

  Fly   361 LAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSAD-IWSVNATELT 424
            |.||..:.||||||.....|:||.|.|::|:|:|.||..|:......|..:..| |.|:...||.
Zfish   359 LGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELV 423

  Fly   425 PLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRCASRDLDFIQFHGL 489
            ..:..::::|||...|...|::..|:....|:.:::|.|:|:|:|||||||..:.:|.:.|:|.|
Zfish   424 DKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLRVEAHNLTWYQYHCL 488

  Fly   490 DTWGLLIAITFVSLLIVVILIKCLQRVFV---SLISKIRKNRAE 530
            |.:..|   |.|..|::.|..| :.:.|:   ...|| ||::.|
Zfish   489 DVFAFL---TTVLTLVLYICFK-MAKFFIMRCCFRSK-RKSKKE 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	145/494 (29%)
ugt2b5	NP_001170816.3	None