Protein Alignment Ugt35A1 and ugt1b5

DIOPT Version :10

• Sequence 1: NP_524314.2
• Gene: Ugt35A1 / 41334
• FlyBaseID: FBgn0026315
• Length: 537
• Species: Drosophila melanogaster
• Sequence 2: NP_001170813.1
• Gene: ugt1b5 / 100384899
• ZFINID: ZDB-GENE-080227-14
• Length: 528
• Species: Danio rerio
• Alignment Length: 574
• Identity: 160/574 - (27%)
• Similarity: 268/574 - (46%)
• Gaps: 93/574 - (16%)

  Fly     2 GGIFSVTGLGILLIGLIWLFAANADEGVQSSRI--LAVFPFPGRSQYIFAEQFMKELAHRGHNVT 64
            |.||:      |::|::...|.|......||..  |.|.|..| |.:...:...:|:..|||.|.
Zfish     3 GVIFN------LVVGVVCSAAMNQKPSRNSSWTGKLLVVPMDG-SHWTGVKAVAEEMGRRGHTVI 60

  Fly    65 VINTFGSDKNEPNFRVIGAK--------KIHEIMAAFGNADYTQTASQWQMLTMTTQ-------- 113
            |:....|.:..|....|..|        .:::::|...|   |.:|.:..:|...|.
Zfish    61 VVIPEISMRLGPGKHYITKKFPVKYKPDVLNQMIAKLVN---TLSAPEQSLLKRVTSNIYNFGKV 122

  Fly   114 ---FLNLLTTSILDDAAVKDLLNSGEKFDLVIME-AVQTEALFGLIQHFGAETI----GISSYGT 170
               |:: .|.|:..:..:.:.|.. :.||.|:.: |:.|.|:  |..:.....:    |:.....
Zfish   123 VDYFIS-TTESLFQEQELIEFLRD-QNFDAVLTDPAMPTGAI--LAYNLSVPAVYMLRGLMCESK 183

  Fly   171 DTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVM------------------WLHK 217
            .|...:      |.||.|.|.:..::.|:|.:|:||.. ||:|                  :||:
Zfish   184 ATACPD------PPSYIPRLFTQNSDHMNFGERLMNTL-ASLMEPLMCKLKFSAFEEVTSKFLHR 241

  Fly   218 RIVHLPSQRDLYAKYFPTARKSLDEVLDSFALMLLGQHFSLSYPRPYLPNMIEVGGLHLQQKRKV 282
            .:                   |:.|:|.:.|:.|:...|:|.:|:|.:||:..:||::.:..
Zfish   242 DV-------------------SMTEILSTGAVWLMRYDFTLEFPKPLMPNITNIGGINCEVN--- 284

  Fly   283 QPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQRVLWKFEDDQLPEKP 346
            .||.||:.|||..| |.|::.||:||.:.|  :|.....:..:.|:.:||||||::..:.....|
Zfish   285 NPLTKEVEEFVNGSGEHGIVVFSLGSLVSS--MPKEKADIFFKAFSMIPQRVLWRYTGEIPNNVP 347

  Fly   347 DNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGL 411
            :||.:.||.||.|:|.||..:.||||||.....|.|..|.|::.||:|.||..||.|....|.|:
Zfish   348 ENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVATRGVGV 412

  Fly   412 SADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHKGAKHLRC 476
            ...|..:....|...:..:::|.||....|..|.:..|:....|:.|::|||:|:|||||.|||.
Zfish   413 ILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGADHLRP 477

  Fly   477 ASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAE 530
            |:.:|:::|:|.||..|.::.|.   |::.:.::||....:.....|.:|.:.:
Zfish   478 AAHELNWLQYHSLDVIGFMLLIV---LIVTLAMLKCCSLCWRRCCRKTQKRKED 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35A1	NP_524314.2	Glycosyltransferase_GTB-type	19..474	CDD:471961	139/499 (28%)
ugt1b5	NP_001170813.1	UDPGT	30..524	CDD:278624	150/535 (28%)