Protein Alignment Ugt35B1 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 546
• Identity: 186/546 - (34%)
• Similarity: 280/546 - (51%)
• Gaps: 59/546 - (10%)

  Fly     1 MLALRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNA------FPQ 59
            :.:|:|..|.::|..:      :.|:|..| |.::||...:.||..:.|.||.:.|      .|.
Mouse     7 LCSLQISLLGMSLGGN------VLIWPMEG-SHWLNVKIIIDELLRKEHNVTVLVASGALFITPS 64

  Fly    60 K-KPVVNFRDVFIPDVFNNYKELINEL--------SGPMNLW----QENNFINKF-FVSVTRC-- 108
            . .|.:.|....:|......:.:|.:.        ..|..:|    :....|.:| .||...|
Mouse    65 SISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDG 129

  Fly   109 VLTNKEVTETLLPPGKDHFDLIIVEALRSDAYYG----FAAHFNAPIIGISTFGTDWNIDALVGN 169
            ||.|:::...|   .|:.|     |.|.||..:.    .|.....|.|....|.....::...|.
Mouse   130 VLKNEKLMSKL---QKEKF-----EVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGK 186

  Fly   170 -ESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKR-VQLT 232
             ..|.||.|.....|||:|:|.:|:.||:...:.  :|.|..:.:|   :..|:.:|..| ..|.
Mouse   187 VPFPPSYVPAILSELTDQMSFTDRVRNFISYRMQ--DYMFETLWKQ---WDSYYTKALGRPTTLC 246

  Fly   233 DLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPA-PLPKDLEEFIQGSGEHGVIYFSLG 296
            :......:.|:..::...|||||:||...|||||.  ||| ||||::|||:|.|||||::.||||
Mouse   247 ETMGKAEIWLMRTYWDFEFPRPYLPNFEFVGGLHC--KPAKPLPKEMEEFVQTSGEHGIVVFSLG 309

  Fly   297 SNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGK-PSNVFISKWFPQPDILAHPKVKLFI 360
            |.|  |:|..::.:||....|.:||:|||::: .|:|.. .||..:..|.||.|:|.|||.:.||
Mouse   310 SMV--KNLTDEKANLIASALAQIPQKVLWRYK-GKIPDTLGSNTRLFDWIPQNDLLGHPKTRAFI 371

  Fly   361 THGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPR 425
            ||||.....|:|:||.|::|:|.|.||..|:......|..:.::..|||..:|...:..::.||.
Mouse   372 THGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLNALRTVINEPS 436

  Fly   426 FAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLL---G 487
            :.:.|.::|..:.|||:.|||.|::|.|:|:|||||.|:|||..||.:|.||||||||.||   .
Mouse   437 YKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLDVIGFLLACVA 501

  Fly   488 GALLLVA-IIVGVLGKLTDFGNAKKK 512
            .|:|||| ..:.:..|:...|..||:
Mouse   502 SAILLVAKCCLFIFQKVGKTGKKKKR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	129/313 (41%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	178/519 (34%)