DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and UGT85A1

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_173656.1	Gene:	UGT85A1 / 838846	AraportID:	AT1G22400	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	521	Identity:	106/521 - (20%)
Similarity:	184/521 - (35%)	Gaps:	160/521 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 PFPGPSQYINVVPYLKELANRGHQVTSVNA------FPQKK--------PVVNFRDVF--IPD-- 73
            |:|.......::...|.|..||..||.||.      |.:.:        |...|..:.  :|:
plant    18 PYPAQGHINPMMRVAKLLHARGFYVTFVNTVYNHNRFLRSRGSNALDGLPSFRFESIADGLPETD 82

  Fly    74 -------------VFNN----YKELINELSGPMNLWQENNFINKFFVSVTRCVLTNKEVTETLLP 121
                         ...|    ::||:..::...|:...:..::...:|.|..|.....|.|.|..
plant    83 MDATQDITALCESTMKNCLAPFRELLQRINAGDNVPPVSCIVSDGCMSFTLDVAEELGVPEVLFW 147

  Fly   122 PGKD-------HFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLA 179
            ....       ||.|.|.:.|             .|:...|....::..|.::      .:.|
plant   148 TTSGCAFLAYLHFYLFIEKGL-------------CPLKDESYLTKEYLEDTVI------DFIP-- 191

  Fly   180 TGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLN 244
                |.:...|:.:.:|:.||    |...|.:|     :|....|.:||.         |.::||
plant   192 ----TMKNVKLKDIPSFIRTT----NPDDVMIS-----FALRETERAKRA---------SAIILN 234

  Fly   245 -----QHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEE--------------------FIQG 284
                 :|..:...:..:|.:..||.||:...     :::||                    ::..
plant   235 TFDDLEHDVVHAMQSILPPVYSVGPLHLLAN-----REIEEGSEIGMMSSNLWKEEMECLDWLDT 294

  Fly   285 SGEHGVIYFSLGS-NVLSKDLPADRKDLILKTF--ASLPQRVLWKFEDDKLPGKPSNV------- 339
            ..::.|||.:.|| .|||.      |.|:...:  |...:..||....|.:.|:.:.|
plant   295 KTQNSVIYINFGSITVLSV------KQLVEFAWGLAGSGKEFLWVIRPDLVAGEEAMVPPDFLME 353

  Fly   340 -----FISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRAT---Q 396
                 .::.|.||..:|:||.:..|:||.|..|.:||:..|.|::..|||.||.:|.:...   .
plant   354 TKDRSMLASWCPQEKVLSHPAIGGFLTHCGWNSILESLSCGVPMVCWPFFADQQMNCKFCCDEWD 418

  Fly   397 AGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWW---TEYVLRH 458
            .|..:|.|       ..:|.:|.:::|....:..::|.|:           |:.|   .|....|
plant   419 VGIEIGGD-------VKREEVEAVVRELMDGEKGKKMREK-----------AVEWQRLAEKATEH 465

  Fly   459 K 459
            |
plant   466 K 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	106/521 (20%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	101/495 (20%)
UGT85A1	NP_173656.1	Glycosyltransferase_GTB_type	14..453	CDD:299143	101/506 (20%)
UGT85A1	NP_173656.1	MGT	20..454	CDD:273616	101/505 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050