Protein Alignment Ugt35B1 and Ugt2b35

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001004271.1
• Gene: Ugt2b35 / 83808
• RGDID: 620895
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 173/548 - (31%)
• Similarity: 287/548 - (52%)
• Gaps: 58/548 - (10%)

  Fly     1 MLALRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVT----SVNAFPQKK 61
            :|.|:|.|..    .|....::| ::|.. .|.::|:...|:||..:||:||    |.:.|...|
  Rat     9 LLLLQISFCF----KSGNCGKVL-VWPME-YSHWMNIKIILEELVQKGHEVTVLRPSASVFLDPK 67

  Fly    62 PVVNFRDVFIPDVFNNYKELINELSGPMNLW----------------QEN-NFINKFFVSVTRCV 109
            ...:.:.|..|..|::: :|.|..:..:|:|                |:. :..:.:.::|.:..
  Rat    68 ETSDLKFVTFPTSFSSH-DLENFFTRFVNVWTYELPRDTCLSYFLYLQDTIDEYSDYCLTVCKEA 131

  Fly   110 LTNKEVTETLLPPGKDHFDLIIVEALRSDAYYG-----FAAHFNAPIIGISTFGTDWNIDALVGN 169
            ::||:.. |.|...|  ||::..:|:      |     .|.....|.:....|...:.|:..:|.
  Rat   132 VSNKQFM-TKLQESK--FDVVFSDAI------GPCGELIAELLQIPFLYSLRFSPGYTIEKYIGG 187

  Fly   170 E-SPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKR-VQLT 232
            . .|.||.|:...||..:|||:||:.|.    :..|.:.|...:.:||.:..::.:...| ..|.
  Rat   188 VLFPPSYVPMIFSGLAGQMTFIERVHNM----ICMLYFDFWFQTFREKKWDPFYSKTLGRPTTLA 248

  Fly   233 DLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPA-PLPKDLEEFIQGSGEHGVIYFSLG 296
            ::.....:.|:..::.|.||.|..||:..:||||.  ||| |||||:|:|:|.||||||:.||||
  Rat   249 EIMGKAEMWLIRSYWDLEFPHPISPNVDYIGGLHC--KPAKPLPKDIEDFVQSSGEHGVVVFSLG 311

  Fly   297 SNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFIT 361
            |.|  :::..::.::|....|.:||:|||:|:..|.|....|..:.||.||.|:|.|||.|.|:|
  Rat   312 SMV--RNMTEEKANIIAWALAQIPQKVLWRFDGKKPPTLGPNTRLYKWLPQNDLLGHPKTKAFVT 374

  Fly   362 HGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRF 426
            |||.....|:||||.|::|:|.|.:|..|:......|..:.::..||::.::...:|.::..|.:
  Rat   375 HGGANGIYEAIHHGIPMIGIPLFGEQHDNIAHMVAKGAAVEVNFRTMSKSDMLNALEEVINNPFY 439

  Fly   427 AQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALL 491
            .:.|..:|..:.|||..|||.|::|.|:|:|||||.|:|..|.:|.::.||||||||.||  ..:
  Rat   440 KKNAMWLSTIHHDQPTKPLDRAVFWIEFVMRHKGAKHLRSLGHNLPWYQYHSLDVIGFLL--TCV 502

  Fly   492 LVAIIVGV---LGKLTDFGNAKKKLKSK 516
            .|.:::.:   |.....|...:||.|::
  Rat   503 AVTVVLALKCFLFVYRFFVKKEKKTKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	120/312 (38%)
Ugt2b35	NP_001004271.1	UDPGT	24..527	CDD:278624	166/524 (32%)