DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt8

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	XP_002934292.2	Gene:	ugt8 / 779534	XenbaseID:	XB-GENE-960667	Length:	537	Species:	Xenopus tropicalis

Alignment Length:	525	Identity:	153/525 - (29%)
Similarity:	263/525 - (50%)	Gaps:	63/525 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QAARILAIFPFPGPSQ-YINVVPYLKELAN----RGHQVTSVNA----FPQKKPVVNFRDVFIPD 73
            :||:||.:.|....|. ||     .|.||:    :|||...:.:    .||..   :::....|.
Frog    19 KAAKILIVPPIMFESHLYI-----FKTLASALHEQGHQTVFLASEGRDIPQSS---HYQVQRYPG 75

  Fly    74 VFNN-------YKELINELSGPMNLWQENNFINKFFVSVTRC--VLTNKEVTETLLPPGKDHFDL 129
            :||:       ..:::|..||.....:..:.::.:   ...|  ::.|.::...|   .::.|||
Frog    76 IFNSSTSDNFLQSKMMNIFSGRFTALELFDILDHY---SKNCDIMVGNLDLMRRL---KQEQFDL 134

  Fly   130 IIVEALRSDAYYGFAAHFNAPIIGI--STFGTDWNIDALVGNESPLSYTPLATGGLTDRMTFLER 192
            ::|:   .:...||..   |.|:.:  :.|.|.....|.||..:||:|.|.....|||.|..|:|
Frog   135 LLVD---PNEMCGFVI---ANILDVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSMLTDNMNLLDR 193

  Fly   193 LSNFVDTTVAWLNYRFVHMSEQEKMYAKY--FPEASKRVQLTDLNRNFSLVLLNQHFSLSFPRPY 255
            :.|.....::.:...|:.:.:.:::..||  |...|    :.:|.:...|.:|....:|.||||.
Frog   194 IKNTFVYLISRIGVNFLVLPKYDRIMQKYNIFSTRS----MYELVQGSCLWMLCTDIALEFPRPT 254

  Fly   256 VPNMIEVGGLHISHKP-APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASL 319
            :||::.|||  |..|| :|||:||:.::....|:|.:..|.|:.|  |.|..|..:.:....|.|
Frog   255 LPNVVYVGG--ILTKPVSPLPQDLQTWVDNVDENGFVLVSFGAGV--KYLSEDIANKLAGALARL 315

  Fly   320 PQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFF 384
            ||:|:|:|...|.....:|..:.:|.||.|:|.|||:|.|::||||....|:::||.||:|:|.|
Frog   316 PQKVIWRFSGTKPRNLGNNTKLIEWIPQNDLLGHPKIKTFLSHGGLNGIFEAMYHGVPVVGIPLF 380

  Fly   385 YDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAI 449
            .|.:..:.|....|.|:.|:...:|:..|..::..::....:.|.|.::|..::|||..|:..|:
Frog   381 GDHYDTMTRVQAKGMGILLEWKKITEDTLFASLTEVIHNQSYQQQAVKLSTIHKDQPGHPVSRAV 445

  Fly   450 WWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAI---IVGVLGKLTDFGNAKK 511
            :|..|:|||.||.|:|.|..::.|:.|..|||:.:|    |.:|.|   .:.:|.|.     .:|
Frog   446 YWINYILRHNGADHLRAAIHNVSFYQYFLLDVVLLL----LFVVTIAWYFISMLAKY-----MRK 501

  Fly   512 KLKSK 516
            .::||
Frog   502 SMRSK 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	137/470 (29%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	120/434 (28%)
ugt8	XP_002934292.2	Glycosyltransferase_GTB-type	21..472	CDD:415824	139/478 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	243	1.000	Domainoid score	I2165
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9349
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.000