Protein Alignment Ugt35B1 and Ugt2b1

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_690024.1
• Gene: Ugt2b1 / 71773
• MGIID: 1919023
• Length: 529
• Species: Mus musculus
• Alignment Length: 550
• Identity: 180/550 - (32%)
• Similarity: 275/550 - (50%)
• Gaps: 74/550 - (13%)

  Fly    16 SMQAARILAIFPF-----PG--------PSQY---INVVPYLKELANRGHQVT------SVNAFP 58
            ||:.|.:..:..|     ||        |::|   ||:...|.||..|||.||      |:...|
Mouse     2 SMKQASVFLLIQFICYIRPGACGKVLVWPTEYSHWINMKIILDELVQRGHDVTVLISSASILIGP 66

  Fly    59 QKKPVVNFRDVFIP----DVFNNYKELIN----ELSGPMNLWQENNFINK-------FFVSVTRC 108
            ..:..:||.....|    |:...:::.:.    ||. .:..|...:.:.|       ...|..:.
Mouse    67 SNESSINFEIYSAPLSKDDLEYAFEKWVGNWTYELK-KLPFWTSYSKLQKISSEYSDMIESFCKA 130

  Fly   109 VLTNKEVTETLLPPGKDHFDLIIVEA------LRSDAYYGFAAHFNAPIIGISTFGTDWNIDALV 167
            |:.||.:.:.|   ....||:::.:|      |.|:.       ...|::....|...:..:...
Mouse   131 VVWNKSLMKKL---QGSKFDVVLADALVPCGELLSEL-------LKTPLVYSLRFCPGYKCEKYS 185

  Fly   168 GN-ESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKR-VQ 230
            |. ..|.||.|:....|:|.|||.||:.|.:..    |.:.|...:..||.:.:::.:...| ..
Mouse   186 GGLPLPPSYVPVVLSELSDHMTFAERVKNMLQV----LLFDFWFQTFNEKSWNQFYSDVLGRPTT 246

  Fly   231 LTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPA-PLPKDLEEFIQGSGEHGVIYFS 294
            ||::.....:.|:...:.|.||.|::||...|||||.  ||| ||||::|||:|.||||||:.||
Mouse   247 LTEMMGKADIWLVRTFWDLKFPHPFLPNFDFVGGLHC--KPAKPLPKEMEEFVQSSGEHGVVVFS 309

  Fly   295 LGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLF 359
            |||.|  |::..::.:::....|.:||:|||:|:..|.....||..:.||.||.|:|.|||.|.|
Mouse   310 LGSMV--KNIKEEKANVVASALAQIPQKVLWRFDGKKPDTLGSNTRLYKWIPQNDLLGHPKTKAF 372

  Fly   360 ITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEP 424
            |.|||.....|:|:||.|::|:|.|.||..|:......|..:.:|..||:..:|...::.::.:|
Mouse   373 IAHGGTNGIYEAIYHGIPIVGIPLFGDQPDNINHIVAKGAAVRVDFDTMSTTDLLTALKTVINDP 437

  Fly   425 RFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGA 489
            .:.:.|.::|..:.||||.|||.|::|.|||:|:|||.|:|.|..||.:|.||||||||.|
Mouse   438 SYKENAMRLSRIHHDQPMKPLDRAVFWIEYVMRNKGAKHLRPALHDLTWFQYHSLDVIGFL---- 498

  Fly   490 LLLVAIIVGVLGKLTDF-----GNAKKKLK 514
            |:.|..:|.::.|...|     .|..||.|
Mouse   499 LVCVVAVVFIIAKCCLFCCHKTANMGKKKK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	126/312 (40%)
Ugt2b1	NP_690024.1	UDPGT	24..527	CDD:278624	172/525 (33%)