Protein Alignment Ugt35B1 and Ugt1a5

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001034638.1
• Gene: Ugt1a5 / 574523
• RGDID: 1583689
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 557
• Identity: 168/557 - (30%)
• Similarity: 260/557 - (46%)
• Gaps: 86/557 - (15%)

  Fly     7 GFLLL--TLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQ-----------VTSVNAFP 58
            |.|||  .||.: :..::| :||..| |.::::...::||..||||           :...:.|.
  Rat    12 GLLLLLYALPWA-EGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQAVVLAPEVTVHIKEEDFFT 73

  Fly    59 -QKKPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFF-----------VSVTRC--V 109
             |..||...|..|...:..|.|.          :::..|::..|.           |.:..|  :
  Rat    74 LQTYPVPYTRQGFRQQMMRNIKV----------VFETGNYVKTFLETSEILKNISTVLLRSCMNL 128

  Fly   110 LTNKEVTETLLPPGKDHFDLIIVEALRS-----DAYYGFAAHFNAPII--GISTFGTDWNIDALV 167
            |.|..:.:.|   ....||:::.:.:..     ..|.|....|....|  ||.:..|..
  Rat   129 LHNGSLLQHL---NSSSFDMVLTDPVIPCGAVLAKYLGIPTVFFLRYIPCGIDSEATQC------ 184

  Fly   168 GNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEAS----KR 228
              ..|.||.|.....|:|.||||:|:.|.:....  |.| ..|.|     :.:|...||    :.
  Rat   185 --PKPSSYIPNLLTMLSDHMTFLQRVKNMLYPLA--LKY-ICHFS-----FTRYESLASELLQRE 239

  Fly   229 VQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYF 293
            |.|.::..:.|:.|....|...:|||.:|||:.:||::...| .||.::.|.::..|||||::.|
  Rat   240 VSLVEVLSHASVWLFRGDFVFDYPRPVMPNMVFIGGINCVIK-KPLSQEFEAYVNASGEHGIVVF 303

  Fly   294 SLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKL 358
            ||||.|  .::|..:...|.:....:||.|||::...:......|..:.||.||.|:|.|||.:.
  Rat   304 SLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARA 366

  Fly   359 FITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKE 423
            ||||.|.....|.|.:|.|::.:|.|.||..|.:|....|.|:.|:...||..:|:..::.::..
  Rat   367 FITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINN 431

  Fly   424 PRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGG 488
            ..:.:...::|..::|:|:.|||.|::|.|||:|||||.|:|.|..||.::.||||||||.||..
  Rat   432 KSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAI 496

  Fly   489 ALLLVAIIVGVL---------GKLTDFGNAKKKLKSK 516
            .|.:|.|:....         ||    |..||..|||
  Rat   497 VLTVVFIVYKSCAYGCRKCFGGK----GRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	111/314 (35%)
Ugt1a5	NP_001034638.1	UDPGT	26..522	CDD:278624	157/533 (29%)