DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	158/500 - (31%)
Similarity:	251/500 - (50%)	Gaps:	46/500 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 KELANRGHQVTSVNAFPQKKPVVNFRD---VFIPDVFNNYKELINELSGPMNLWQENNFINKFFV 103
            |.||..||.||.|:   ..:|.|..:|   :.:|......:.|.|:::....  .:||.|...::
  Fly     5 KALAEAGHNVTVVS---MMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAG--SKNNIITTMYL 64

  Fly   104 SVTRCVLTNKEVTETLLPPG-----KDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDW-- 161
            .:....:......:.|..|.     :..|||:|:.:..:|...|.|.....|:|      .||
  Fly    65 LLNGLDVMVTSQADLLKDPRFQRVFETKFDLMILGSFFNDFQLGVAGKLKVPVI------VDWMI 123

  Fly   162 ----NIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTV-----AWLNYRFVHMSEQEKM 217
                .||..|.|.|.:||.|..:...|..|:|.:|..|.|...:     ...||:|      .::
  Fly   124 PSNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKF------NRI 182

  Fly   218 YAKYFPEASKRVQLTDLNRNFSLVLLNQHFSLSFP-RPYVPNMIEVGGLHISHKPAPLPKDLEEF 281
            |.:.|.:..... |:::.:|.|:|.:..|.....| ||.||.:|||||:.:..:|.|||:|:|:|
  Fly   183 YNEIFTDKDMPT-LSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQF 246

  Fly   282 IQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFED-DKLPGKPSNVFISKWF 345
            ::.|.: |.|:.|.|||:.|..:..:...::.|..:.|.|.|:||:|| :..||..||:|...|.
  Fly   247 MENSSQ-GAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWL 310

  Fly   346 PQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQ 410
            ||.||||||..|||:||.|..|..||.:||.|::.||.|.|..||......:|:|:.||..|:|:
  Fly   311 PQDDILAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITE 375

  Fly   411 QELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFA 475
            ...:|.|..:|:..::.|..|:.|..|||:|::|..:.::|.:|||||.||.:::.....:||..
  Fly   376 DTFREAINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVE 440

  Fly   476 YHSLDVIGVLLGGALLLVAI----IVGVLGKLTDFGNAKKKLKSK 516
            .|:||:..::|...:.||.:    :..:..||  .|.||...:.|
  Fly   441 LHNLDIYALVLAILIFLVFLTRLTVKFLFSKL--LGKAKVPARKK 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	144/444 (32%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	131/416 (31%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	155/492 (32%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	143/445 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445739
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	8	7.840