Protein Alignment Ugt35B1 and Ugt1a3

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_958827.1
• Gene: Ugt1a3 / 396551
• RGDID: 1549728
• Length: 531
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 160/546 - (29%)
• Similarity: 273/546 - (50%)
• Gaps: 64/546 - (11%)

  Fly     7 GFLLL--TLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRDV 69
            |.|||  .||.: :..::| :||..| |.::::...::||..||||  :|...|:....:...|.
  Rat    12 GLLLLLCALPWA-EGGKVL-VFPMEG-SHWLSMRDVVRELHARGHQ--AVVLAPEVTVHIKEEDF 71

  Fly    70 F------IPDVFNNYKELINELSGPMNLWQENNF--------------INKFFVSVTRCVLTNKE 114
            |      :|.....|:   :.|.|.:..:.|..|              ::.|:|...|.:|.|..
  Rat    72 FTLQTYPVPYTKEEYR---HHLLGHLQNFFETEFSLKLVLQRMAAVNNVSTFYVRSCRGLLHNTA 133

  Fly   115 VTETLLPPGKDHFDLIIVEALRSDAYYG----FAAHFNAP-IIGISTFGTDWNIDALVGNESPLS 174
            :.::|   ....||:::     :|.::.    .|.:...| :..:.:...:...:| ..:.:|.|
  Rat   134 LIQSL---NSSSFDVVL-----TDPFFPCGAVLAMYLRVPAVFFLQSMLCELEFEA-TNSPNPSS 189

  Fly   175 YTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFS 239
            |.|......:|.|:||:|:.|.: ..|.|:....|:.....::.:...   .:.|.:.::.|:.|
  Rat   190 YIPRLLTLNSDHMSFLDRVKNML-YPVPWMYLCHVNYGSLARLASDLL---QREVSVVEILRHAS 250

  Fly   240 LVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDL 304
            :.||.:.|...:|||::|||:.:||::.::: .||.::.|.::..|||||::.|||||.|  .::
  Rat   251 VWLLRKDFVFYYPRPFMPNMVFIGGINCANR-KPLSQEFEAYVNASGEHGIVVFSLGSMV--SEI 312

  Fly   305 PADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTI 369
            |..:...|.:....:||.|||::...:......|..:.||.||.|:|.|||.:.||||.|.....
  Rat   313 PEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIY 377

  Fly   370 ESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMS 434
            |.|.:|.|::.:|.|.||..|.:|....|.|:.|:...||..:|:..::.::....:.:...::|
  Rat   378 EGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLS 442

  Fly   435 ERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAIIVGV 499
            ..::|:|:.|||.|::|.|||:|||||.|:|.|..||.::.||||||||.||...|.:|.|:...
  Rat   443 SLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKS 507

  Fly   500 L---------GKLTDFGNAKKKLKSK 516
            .         ||    |..||..|||
  Rat   508 CAYGCRKCFGGK----GRVKKSHKSK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	105/310 (34%)
Ugt1a3	NP_958827.1	UDPGT	26..522	CDD:278624	149/522 (29%)