Protein Alignment Ugt35B1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_964007.2
• Gene: Ugt1a1 / 394436
• MGIID: 98898
• Length: 535
• Species: Mus musculus
• Alignment Length: 559
• Identity: 167/559 - (29%)
• Similarity: 270/559 - (48%)
• Gaps: 79/559 - (14%)

  Fly     2 LALRIGFLLLTL--PASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSV----NAFPQK 60
            |.|.:.:|||.:  |::..|.|:| :||..| |.:::::..:::|..:||:|..:    :...::
Mouse    10 LLLLLPYLLLCVFGPSASHAGRLL-VFPMDG-SHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKE 72

  Fly    61 KPVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNF---INKFFVSVTR--------C--VLTN 112
            ......|...:|....|....:.||.  ...:.:::|   :.|.::.|.|        |  :|.|
Mouse    73 GSFYTLRKFPVPFQKENVTATLVELG--RTAFNQDSFLLRVVKIYMKVKRDSSMLLAGCSHLLHN 135

  Fly   113 KEVTETLLPPGKDHFDLIIVEALRSDAYYG----FAAHFNAPIIGISTFGTDWNIDALVGNES-- 171
            .|...:|   .:.|||     ||.:|.:..    .|.:...|.:....     .:...:.:|:
Mouse   136 AEFMASL---EESHFD-----ALLTDPFLPCGSIVAQYLTVPTVYFLN-----KLPCSLDSEATQ 187

  Fly   172 ---PLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEAS------- 226
               ||||.|.:....:|||.||:|:.|.:           :.:||.......|.|..|
Mouse   188 CPVPLSYVPKSLSFNSDRMNFLQRVKNVL-----------LAVSENFMCRVVYSPYGSLATEILQ 241

  Fly   227 KRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVI 291
            |.|.:.||....|:.|:...|...:|||.:|||:.:||::...| .||.::.|.::..|||||::
Mouse   242 KEVTVQDLLSPASIWLMRSDFVKDYPRPIMPNMVFIGGINCLQK-KPLSQEFEAYVNASGEHGIV 305

  Fly   292 YFSLGSNVLSKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKV 356
            .|||||.|  .::|..:...|.:....:||.|||::...:......|..:.||.||.|:|.|||.
Mouse   306 VFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKT 368

  Fly   357 KLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILL 421
            :.||||.|.....|.|.:|.|::.:|.|.||..|.:|....|.|:.|:...||..:|:..::.::
Mouse   369 RAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVI 433

  Fly   422 KEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLL 486
            ....:.:...::|..::|:|:.|||.|::|.|||:|||||.|:|.|..||.::.||||||||.||
Mouse   434 NNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLL 498

  Fly   487 GGALLLVAIIVGVL---------GKLTDFGNAKKKLKSK 516
            ...|.:|.|:....         ||    |..||..|||
Mouse   499 AIVLTVVFIVFKCCAYGCRKCFGGK----GRVKKSHKSK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	111/322 (34%)
Ugt1a1	NP_964007.2	UDPGT	30..526	CDD:278624	155/530 (29%)