DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and ugt-35

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001023694.1	Gene:	ugt-35 / 3565443	WormBaseID:	WBGene00044286	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	571	Identity:	136/571 - (23%)
Similarity:	238/571 - (41%)	Gaps:	106/571 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVV-----NFR 67
            ||:..|..:.::...|...|....|.:..:......|:..||.||.:      .|::     ||:
Worm    10 FLISILFQNSKSVNFLVYCPLFAHSHHTFLAKIADTLSEEGHNVTFL------APIIVQKYENFK 68

  Fly    68 ------DVFI--PDVFNNYKEL--INELSGPMNL---WQENNFI------NKFFVSVTRCVLTNK 113
                  |:..  ||     :||  :.|:.|....   |.|...:      .|.|..:...:..|.
Worm    69 YLKHTTDIIYIQPD-----EELKKLGEIMGSAGFSKYWTEEPSVFSMIPSIKLFQKMFHKIYENL 128

  Fly   114 EVTETLLPPGKDH-FDLIIVEALRSDAYYGFAAHFNA----PIIGISTFGTDWNI-DALVGNES- 171
            ....::|...||. ||.:|.|.|.          |||    ..:||.|....::: ..:|.::|
Worm   129 RADLSILDSLKDRKFDAMIYEVLA----------FNAIAIQQYLGIKTLYPTFSVTHGMVLSKSI 183

  Fly   172 --PLSYTPL--ATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLT 232
              |.|...|  |.....::|.|.|||.|   |..|::...|:...:.......|:     .:.|.
Worm   184 GEPASPATLSSALSPYGEKMNFQERLMN---TVCAFIYQVFMKPPKMISYSHPYY-----EIDLK 240

  Fly   233 DLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGV------- 290
            :.....|.|.||.:..|.||||.:...:.:||:.::.......:..:|:      |.:
Worm   241 EAESKASFVFLNSNPYLDFPRPMLTKTVLIGGISVNTSQIREERLSDEY------HNILNIRVKT 299

  Fly   291 IYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKL--PGKPSNVFISKWFPQPDILA 352
            :..|.||.:||.|:|...|.:|:|.....|. ..:||:|.|:|  .....|:...||.||..:||
Worm   300 VLISFGSIMLSTDMPDRYKSIIVKVIEEFPNVTFIWKYESDELDFANNLKNLHFFKWIPQTALLA 364

  Fly   353 HPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQ-QELKET 416
            ..::..||||.||.|..|..:.|||.:.:|.|.||..|.:...:....:.|:...:.. ::|:.:
Worm   365 DSRLSAFITHAGLGSINELSYMGKPAILVPIFADQLRNAKMLVRHNGSISLEKQDLGNFEKLRVS 429

  Fly   417 IEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQD-----LGFF 474
            :..:||:..|.:.|..::.:..:||:||       .|.:::|.  ||....:...|     :.||
Worm   430 LAKILKDNSFQENAEILARQLNNQPISP-------RELLIKHATFGAEFGELPSLDPYSRQMSFF 487

  Fly   475 AYHSLDV---IGVLLGGALLL------VAIIVGVLGKLTDFGNAKKKLKSK 516
            :.:.:|:   :||.|  |:|:      :.:::.:|.|......:::..|:|
Worm   488 SLNMIDIFLFLGVFL--AILVYFLFTFLRLLLNLLLKKKAVEKSQENRKTK 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	123/505 (24%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	111/457 (24%)
ugt-35	NP_001023694.1	Glycosyltransferase_GTB_type	2..464	CDD:299143	120/495 (24%)
ugt-35	NP_001023694.1	UDPGT	34..506	CDD:278624	126/515 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810