DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt-39

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504816.2	Gene:	ugt-39 / 3564933	WormBaseID:	WBGene00017329	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	554	Identity:	121/554 - (21%)
Similarity:	221/554 - (39%)	Gaps:	74/554 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVT-----------SVNAF 57
            :|:.|:|.....::.:...|...|....|...........|.:.||.||           :|:..
Worm     1 MRLLFILFLFFGNVSSFNFLVFCPLFAHSHSKFFATIADSLTDAGHNVTFFTPTIVEKYRNVSYT 65

  Fly    58 PQKKPVVNFRDVFIPDVFNNYKELINELSGP--MNLWQENNFINKFFVSVTRCV--LTNKEVTET 118
            ...|.||:.:    |.  ...||...::|..  :..|.|::...: .:.|.|..  :.|::.|..
Worm    66 KSTKDVVHMK----PS--KKLKEYGEQMSTGDFVRYWTEDSTATE-IIPVVRIFQKMYNEQGTVM 123

  Fly   119 LLPPG------KDHFDLIIVEALRSDAYYGFAAHFNAPIIGISTF------GTDWNIDALVGNES 171
            ....|      |..||:||.||      |.::|:.....:.|.||      ..|.::...:|...
Worm   124 KDNVGILNELKKRKFDVIIFEA------YIYSAYPLMDYLEIPTFIPSVSVAHDTSLAIEIGEPV 182

  Fly   172 PLSYTPLATGGLTDRMTFLERLSN-----FVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQL 231
            ..|..........|:::..||..|     :.|..:.:..:|        .....|.|     :.:
Worm   183 MPSVVSDCLSPFGDKLSITERAFNAFMVPYFDFMIGYPTHR--------SFKPPYNP-----IDI 234

  Fly   232 TDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISH---KPAPLPKDLEEFIQGSGEHGVIYF 293
            ..:....|.|.||.:..:.||||.:...|::||:.:..   :...|.:...|.::  .....:..
Worm   235 RSIVPEASFVFLNSNPFVDFPRPTLTKTIQIGGISVDSNELRSQKLDETWSEILK--LREKTMLV 297

  Fly   294 SLGSNVLSKDLPADRKDLILKTFASLPQRV--LWKFED---DKLPGKPSNVFISKWFPQPDILAH 353
            |.||.:.|||:|...| :.||......:.|  :||:||   |:......|:..:||.||..:||.
Worm   298 SFGSMLYSKDMPFKNK-IALKNAMEKFKNVTFIWKYEDDSSDEFAKGIENIHFAKWVPQTALLAD 361

  Fly   354 PKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQE-LKETI 417
            .::..|:||.||.|..|..:.|||.:..|..:||..|.:...:....:.|....:...| :....
Worm   362 SRLSAFLTHAGLGSINELSYLGKPAILCPQLFDQMRNAKMLVRHNGSIELSKYDLGDSEKIVNAF 426

  Fly   418 EILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVI 482
            :.:|.:..:|:.|.:::|:..:||:.|.:..:...|:..|......:....:.:.|..|..:||.
Worm   427 QAILFDSSYAKNALKLAEQLENQPIKPKEMMVKHAEFAARFGRLPSLDPYSRKMTFIEYFLIDVA 491

  Fly   483 GVLLGGALLLVAIIVGVLGKLTDFGNAKKKLKSK 516
            .:.:   ::|:|::. |:.|:......|..:|.|
Worm   492 AISM---VVLIAVVF-VITKMFKILCNKTSVKGK 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	109/498 (22%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	101/452 (22%)
ugt-39	NP_504816.2	Glycosyltransferase_GTB_type	12..503	CDD:299143	113/522 (22%)
ugt-39	NP_504816.2	UDPGT	29..521	CDD:278624	115/524 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810