DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and F10D2.8

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001309630.1	Gene:	F10D2.8 / 266913	WormBaseID:	WBGene00017334	Length:	494	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	113/549 - (20%)
Similarity:	208/549 - (37%)	Gaps:	113/549 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LRIGFLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVNFRD 68
            :|...::|:|..|..:...|...|..|.|...........|.:.||.||
Worm     1 MRTFLVILSLIYSTYSYNFLVFCPLFGHSHTKFFATIADALTDAGHNVT---------------- 49

  Fly    69 VFIPDVFNNYKEL--------INELSGPMNL---------------W-QENNFINKFFVSVTRCV 109
            .|.|.:...|:.:        :..:..|..|               | ::::|.|.....:.||.
Worm    50 FFTPTIVEKYRNVSYTKLTKDVVHMDAPKKLMEYGEQMESADFSRFWTEDSSFYNVGAADLYRCS 114

  Fly   110 LTNKEVTETLLPPGKDHFDL---IIVEALRSDAYYGFAAHFNAPIIG------ISTFGTDWNIDA 165
            :....:.::|:    |:.::   |...:|..|.|...|  ...|::.      .|.||
Worm   115 IRLNGLFKSLM----DYLNIKTFIPSLSLTHDVYLSKA--IGEPVMPSVVSDVCSPFG------- 166

  Fly   166 LVGNESPLSYTPLATGGLTDRMTFLERLSN-----FVDTTVAWLNYRFVHMSEQEKMYAKYFPEA 225
                               |:::.|||..|     ::|..:.:.    ||    ..:.|.|
Worm   167 -------------------DKLSLLERAFNAFAVPYIDIVLGYP----VH----NTLSAPY---- 200

  Fly   226 SKRVQLTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHI---SHKPAPLPKDLEEFIQGSGE 287
             ..:.:..:....|.:.||.:..|.||||.:...:|:||:.:   ..|...|.....:.:  :..
Worm   201 -TEIDIRTIEPEASFLFLNSNPFLDFPRPTLTKTVEIGGITVDLNQLKSQQLDSKWSDIL--NLR 262

  Fly   288 HGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKLPGKP---SNVFISKWFPQP 348
            ...:..|.||...|||:|.:.|.:|..:...... ..:||:|.:.:....   .|:...||.||.
Worm   263 EKTMLVSFGSVFFSKDMPLENKKVIANSMTEFKNVTFIWKYEGNDIEDFARGIQNIHFVKWVPQT 327

  Fly   349 DILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTM-TQQE 412
            .:||:.::..|.||.||.|..|..:.|||.:..|.|.||..|.:...:....:.|....: ..::
Worm   328 ALLANRRLSAFFTHAGLGSINEVSYLGKPSILCPLFADQMRNAKMLVRHNGSIELSKYDLGNSKK 392

  Fly   413 LKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYH 477
            :.|..:.:|.:..:|:.|::::|:..:||:.|....:...|:..|......:....:.:.|..|.
Worm   393 IIEAFQAILFDSSYAENAQKLAEQLENQPIKPEKMMVKHAEFAARFGRLPSLDPYSRKMSFVEYF 457

  Fly   478 SLDVIGVLLGGALLLVAIIVGVLGKLTDF 506
            .|||..:    .:|::|.:|.||.::..|
Worm   458 LLDVATI----CVLVLACVVFVLTRVVQF 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	101/503 (20%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	92/457 (20%)
F10D2.8	NP_001309630.1	UDPGT	29..492	CDD:278624	106/521 (20%)
F10D2.8	NP_001309630.1	Glycosyltransferase_GTB_type	<215..461	CDD:299143	60/247 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810