Protein Alignment Ugt35B1 and Ugt1a2

DIOPT Version :10

• Sequence 1: NP_524313.2
• Gene: Ugt35B1 / 41333
• FlyBaseID: FBgn0026314
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 550
• Identity: 162/550 - (29%)
• Similarity: 267/550 - (48%)
• Gaps: 72/550 - (13%)

  Fly     7 GFLLL--TLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQ----VTSVNAFPQKKPVVN 65
            |.|||  .||.: :.|::| :.|..| ||::::...::||..||||    .:.|....:.:....
Mouse    14 GLLLLLCALPWA-EGAKVL-VLPMEG-SQWLSMRDVVRELHARGHQTVVLASEVTVHIKGEDFFT 75

  Fly    66 FRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVSV-----------TRCV--LTNKEVTE 117
            .:....|.....|::.|  ||.....::..:|:..||.:.           ..|:  |.||.:.:
Mouse    76 LKTYAFPYTKEEYQQEI--LSDIEKTFKTQHFVKAFFETTASIRNFFDLYSNSCIALLHNKMLIQ 138

  Fly   118 TLLPPGKDHFDLIIVEALRSDAYYGF------AAHFNAPIIGI---STFGTDWNIDALVGNESPL 173
            .|   ....||:|:.:.:       |      |.:...|.:.|   .:.|.::.....   .:|.
Mouse   139 QL---NSSFFDVILTDPI-------FPCGAVLAKYLQIPAVFILRSLSCGIEYEATQC---PNPS 190

  Fly   174 SYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFV---HMSEQEKMYAKYFPEASKRVQLTDLN 235
            ||.|.....|:|.|.||:|:.|.    :.:|..:::   .::..|.:.::..   .:.|.|.::.
Mouse   191 SYIPNLLTRLSDHMDFLQRVQNM----LYYLVLKYICRLSITPYESLASELL---QREVSLVEVL 248

  Fly   236 RNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISHKPAPLPKDLEEFIQGSGEHGVIYFSLGSNVL 300
            .:.|:.|....|.|.:|||.:|||:.:||::...| .||.::.|.::..|||||::.|||||.|
Mouse   249 SHASVWLFRGDFVLDYPRPIMPNMVFIGGINCVTK-KPLSQEFEAYVNASGEHGIVVFSLGSMV- 311

  Fly   301 SKDLPADRKDLILKTFASLPQRVLWKFEDDKLPGKPSNVFISKWFPQPDILAHPKVKLFITHGGL 365
             .::|..:...|.:....:||.|||::...:......|..:.||.||.|:|.|||.:.||||.|.
Mouse   312 -SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSGS 375

  Fly   366 LSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIA 430
            ....|.|.:|.|::.:|.|.||..|.:|....|.|:.|:...||..:|:..::.::....:.:..
Mouse   376 HGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENI 440

  Fly   431 RQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIGVLLGGALLLVAI 495
            .::|..::|:|:.|||.|::|.|||:|||||.|:|.|..||.::.||||||||.||...|.:|.|
Mouse   441 MRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFI 505

  Fly   496 IVGVL---------GKLTDFGNAKKKLKSK 516
            :....         ||    |..||..|||
Mouse   506 VFKCCAYGCRKCFGGK----GRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	Glycosyltransferase_GTB-type	<171..482	CDD:471961	106/313 (34%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	151/526 (29%)