DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt35B1 and ugt-31

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001021756.1	Gene:	ugt-31 / 189771	WormBaseID:	WBGene00021464	Length:	521	Species:	Caenorhabditis elegans

Alignment Length:	535	Identity:	138/535 - (25%)
Similarity:	221/535 - (41%)	Gaps:	78/535 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 FLLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVT------------------SV 54
            |..:.|.|| :...||...|..|.|....:......|...||.||                  :.
Worm     6 FFPILLVAS-EPLNILVYSPVFGGSHSKFMGNIADTLTEAGHNVTFLVSVADVTRRHEIGVKLTK 69

  Fly    55 NAFPQKKPVVNFRDVFIPDVFNNYKELINELSGPMNLW----QENNFIN--KFFVSV--TRCV-- 109
            |.....||..:..||.|.         ::|:..|  ||    :.::|..  :||:.:  |.|.
Worm    70 NVIIVDKPNFSQDDVEID---------MDEVLRP--LWTIQNRPSDFATCFEFFIQMMQTTCAEF 123

  Fly   110 LTNKEVTETLLPPGKDHFDLIIVEALRSDAYYGF--AAHFNAPIIGISTFGTDWNIDALVGNES- 171
            .:|:|:.:.|   .|..|.:.|.|.: |....|:  |......|:..||    .:.:.:|.|..
Worm   124 TSNREIFKKL---SKTEFHVAIAEPV-SICGLGYFDALGIKKTILASST----THYEGVVRNSGE 180

  Fly   172 --PLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKR-VQLT- 232
              .:||.|:......::|...:|.:|:....|...|.        |:|:.:...|..|. ||.|
Worm   181 PVDMSYVPVHGAYFDEKMDIFQRYTNWASEHVLAGNL--------ERMFDQEMSEYRKNLVQSTG 237

  Fly   233 ---DLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHISH---KPAPLPKDLEEFIQGSGEHGVI 291
               ||..:.||:..|.:..|.||||.:...:.:||:.:..   |...||:.:.:.:: ..|:.::
Worm   238 HWRDLIPSASLMFTNSNPYLDFPRPVLQKTVGIGGITVDMEQIKSEKLPEKINKLLE-KREYNML 301

  Fly   292 YFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKL--PGKPSNVFISKWFPQPDILAH 353
             .|.||.|.|..:|...::.||....:.|. ..:||:|.|.|  .....||...||.||..:|.:
Worm   302 -ISFGSMVKSSTMPEKWRNSILSAIRNFPNVTFIWKYESDDLRWAENVENVHFLKWIPQTALLNN 365

  Fly   354 PKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQE-LKETI 417
            |:|..|:|||||.||.|....|||.:.:|.|.||..|.....:.|..|.|....:...| |.:.|
Worm   366 PRVSAFLTHGGLGSTNELAFIGKPSIIVPIFGDQGRNAPMLARHGGALVLQKFDLENAEVLIDFI 430

  Fly   418 EILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVI 482
            ..::.:..:|:.|:.::......|.||.:..:..||:|........|....:.|.:|.....|:.
Worm   431 GKIVFDKSYAKNAKTLANLLNASPFSPKELVVKNTEFVGNFGPLTQMDPYIRKLNWFQRTFADIY 495

  Fly   483 GVLLGGALLLVAIIV 497
            .:|.   |:..:|||
Worm   496 LILF---LVYASIIV 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	130/502 (26%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	117/456 (26%)
ugt-31	NP_001021756.1	UDPGT	28..518	CDD:278624	130/512 (25%)
ugt-31	NP_001021756.1	Glycosyltransferase_GTB_type	<248..472	CDD:299143	67/225 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810