DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and ugt-30

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_506729.1	Gene:	ugt-30 / 187955	WormBaseID:	WBGene00011340	Length:	535	Species:	Caenorhabditis elegans

Alignment Length:	553	Identity:	132/553 - (23%)
Similarity:	227/553 - (41%)	Gaps:	107/553 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 SQYINVVPY-----------LKELAN----RGHQVTSVNAFPQKKPVVNF------------RDV 69
            |..:|::.|           |.:||:    |||.||.:      .||||.            :||
Worm    16 SNCLNILVYAPAFAASHSKFLGKLADTLTERGHNVTYL------MPVVNIAKRDECKGVKITKDV 74

  Fly    70 FIPDV---FNNYKELINELSGPMNLW-------QENNFINKFFVSVTRCV----LTNKEVTETLL 120
            .|.:.   ..:.|:........:::|       ..:..|.:||.|..:..    |:.:::.|.:
Worm    75 VIVEAGEKMLSQKQADTPNDEILDVWWTVQMDSSNSREIFQFFCSDMKIACENFLSRRDIFEDM- 138

  Fly   121 PPGKDHFDLIIVEALRSDAYYGF--AAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATGGL 183
              ...:|||.|:|.: |....||  |......|:..|:...| .|...:|.....||.|......
Worm   139 --KARNFDLAILEPV-SACGLGFVKALGIEKTILASSSVFYD-VILPYIGEPLDYSYVPSGYSVT 199

  Fly   184 TDRMTFLERLSNFVDTTVAWLNYRFVHMS-------EQEKMYAK-----------YFPEASKRVQ 230
            ...::..|:..|       |:..|.:.::       |.| :|.:           .||.|
Worm   200 GQELSLGEKFEN-------WMVSREISIALEGLFDGEME-IYRRLLGHNLTNWRHLFPSA----- 251

  Fly   231 LTDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGLHIS---HKPAPLPKDLEEFIQGSGEHGVIY 292
                    |:..:|.:....||||.:...:.:||:.::   .|...|.::.|: :.....|.::
Worm   252 --------SIFFVNSNPFFDFPRPVLEKTVPIGGISVNMGVRKEDMLTEEWEK-VLNQRPHTML- 306

  Fly   293 FSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDD--KLPGKPSNVFISKWFPQPDILAHP 354
            .|.|:.|:|..:|...:..:|:.|.|.|. ..:||:|.|  .......|::.|||.||.::|...
Worm   307 VSFGTLVMSTHMPKKWRSGLLEAFKSFPNVTFIWKYESDDHSFANGIDNIYFSKWVPQNELLNDN 371

  Fly   355 KVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQE-LKETIE 418
            ::..|::||||.|.:|....|||.|.:|.|.||..|.....:....:.|..:.|...| ||:..:
Worm   372 RLTAFLSHGGLGSIMELAFSGKPALIIPVFADQTRNANTLARHRGAICLHKSQMKNTEVLKKAFK 436

  Fly   419 ILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHSLDVIG 483
            .:|.:..|...:.:::...|:||..|.||.|.:||:|........|...|:.|..|....:|:..
Worm   437 SVLFDASFKNNSLKLAATLRNQPNKPKDTLIKYTEFVGEFGPFPQMDPYGRHLNVFQKSFIDIYT 501

  Fly   484 VLLGGALLLVAIIVGVLGKLTDFGNAKKKLKSK 516
            :::..:.:.||:|..|:.||..:     .:|||
Worm   502 LIIVVSSIFVALIFNVIAKLIQY-----FIKSK 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	119/501 (24%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	108/473 (23%)
ugt-30	NP_506729.1	UDPGT	21..529	CDD:278624	128/546 (23%)
ugt-30	NP_506729.1	Glycosyltransferase_GTB_type	<255..524	CDD:299143	75/270 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810