DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt35B1 and ugt-8

DIOPT Version :9

Sequence 1:	NP_524313.2	Gene:	Ugt35B1 / 41333	FlyBaseID:	FBgn0026314	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_504315.1	Gene:	ugt-8 / 186768	WormBaseID:	WBGene00019234	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	524	Identity:	135/524 - (25%)
Similarity:	217/524 - (41%)	Gaps:	82/524 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLTLPASMQAARILAIFPFPGPSQYINVVPYLKELAN----RGHQVTSVNAFP----------Q 59
            :||.| .|:....||...|..|.|.    |.::.::||    .||.||....|.          :
Worm     9 ILLVL-GSVSCKNILIFNPIFGLSH----VKFISKMANIIADHGHNVTLFQPFHIALKNTEGLIK 68

  Fly    60 KK--PVVNFRDVFIPDVFNNYKELINELSGPMNLWQENNFINKFFVS---VTRCVLTNKEVTETL 119
            .|  .::|    :.||   :|.||:...:.....:.:::.:|...:|   :.:.:....|.|.|.
Worm    69 NKYIEIIN----YYPD---HYDELLKTETATFPAFWDSHLMNNPVLSAFMIPKAIAGEFERTATQ 126

  Fly   120 LPPGK--------DHFDLIIVEALRSDAYYGFAAH-FNAPIIGISTFGTDWN------IDALVGN 169
            |...|        .:||:||.|.......|  .|| .|.|.|.:      |:      .:.:.|.
Worm   127 LLKDKVALDDLKSRNFDVIISETFELTGMY--IAHMLNVPCIPV------WSAVRFTIFNNIFGQ 183

  Fly   170 ESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQL--- 231
            .|.|.|:......|.....|::||::      .:.|:.|....:....|...|.|.:....|
Worm   184 PSSLGYSQQPFSKLAPEAGFIDRLND------VYRNFFFTITMDGMGQYQNDFIEKAVGRPLPYW 242

  Fly   232 TDLNRNFSLVLLNQHFSLSFPRPYVPNMIEVGGL--------HISHKPAPLPKDLEEFIQGSGEH 288
            .||.:...:...|.:..|.|..|....::.:||.        |:...|....|.|||      ..
Worm   243 KDLIKEAPVYFTNSNEYLDFAVPTTATIVHIGGFTMDLEKMKHVDPLPDKYAKILEE------RE 301

  Fly   289 GVIYFSLGSNVLSKDLPADRKDLILKTFASLPQ-RVLWKFEDDKLPGK---PSNVFISKWFPQPD 349
            ..:..|.||.:.|..:|.:.|..|:|.|.|||. ..:||:|.|.:..:   |.||.:.||.||..
Worm   302 STVLISFGSVIRSYQMPDNFKAGIIKMFESLPDVTFIWKYERDDVEFQKKLPKNVHLKKWVPQHS 366

  Fly   350 ILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQ-QEL 413
            :||..:||||:|||||.||:|..:.|||.|.:|.|.||..|.....:.|..:..|...:.. ::|
Worm   367 LLADNRVKLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPENANMLARHGGAISYDKFELADGEKL 431

  Fly   414 KETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHKGAYHMRVAGQDLGFFAYHS 478
            ..||..:::.|::.:.|:::.:....||:.|....:...|:.:..........|...:|..|::.
Worm   432 AITIRDMVRNPKYNKNAQELLKVLSHQPIDPKLNLMKHLEFAMEFPNLRSQVPAINQMGLIAHYY 496

  Fly   479 LDVI 482
            ||||
Worm   497 LDVI 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt35B1	NP_524313.2	egt	8..466	CDD:223071	128/506 (25%)
Ugt35B1	NP_524313.2	MGT	26..438	CDD:273616	118/461 (26%)
ugt-8	NP_504315.1	UDPGT	30..516	CDD:278624	127/502 (25%)
ugt-8	NP_504315.1	egt	<284..462	CDD:223071	61/183 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810